Person:
Martínez Sanz, Elena

First Name

Elena

Last Name

Martínez Sanz

URI

https://hdl.handle.net/20.500.14352/78924

Affiliation

Universidad Complutense de Madrid

Faculty / Institute

Medicina

Department

Anatomía y Embriología

Area

Anatomía y Embriología Humana

Identifiers

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Search Results

Now showing 1 - 10 of 14

Project number: 114
Desarrollo de un sistema interactivo para el estudio de la órbita y su contenido: anatomía microscópica
(2022) Barrio Asensio, María Del Carmen; Arráez Aybar, Luis Alfonso; Catón Vázquez, Francisco Javier; García Serradilla, Moisés; García-Mauriño Múzquiz, José Enrique; Maldonado Bautista, Estela; Martínez Sanz, Elena; Mérida Velasco, José Ramón; Murillo Barrio, Jaime; Murillo González, Jorge Alfonso; Paradas Lara, Irene
Se ha desarrollado un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de la anatomía microscópica de la órbita y su contenido, a través de preparaciones histológicas. Se pretende facilitar el aprendizaje de forma autónoma en español e inglés y, la autoevaluación sobre los conocimientos adquiridos.
Study of the functional relationships between the buccinator muscle and the connective tissue of the cheek in humans
(Annals of Anatomy, 2022) Martínez Sanz, Elena; Catón Vázquez, Francisco Javier; Maldonado Bautista, Estela; Murillo González, Jorge Alfonso; Barrio Asensio, María Del Carmen; Paradas Lara, Irene; García Serradilla, Moisés; Arráez Aybar, Luis Alfonso; Mérida Velasco, José Ramón
Background: The buccinator muscle derives from the mesenchyme of the second pharyngeal arch. In adults, it has a quadrilateral shape, occupying the deepest part of the cheek region. Its function is complex, being active during swallowing, chewing, and sucking. To our knowledge, there are no studies that have specifically analyzed the relationship of the buccinator muscle fibers and neighboring connective tissue of the cheek in humans, neither during development nor in adults. Such relationships are fundamental to understand its function. Thus, in this study the relations of the buccinator muscle with associated connective tissue were investigated. Methods: The buccinator muscle region was investigated bilaterally in 41 human specimens of 8–17 weeks of development. Moreover, four complete adult tissue blocks from human cadavers (including mucosa and skin) were obtained from the cheek region (between the anterior border of the masseter muscle and the nasolabial fold). All samples were processed with standard histological techniques. In addition, subsets of sections were stained with picrosirius red (PSR). Furthermore, immunoreactivity against type I and III collagen was also studied in adult tissues. Results: The buccinator muscle showed direct relationships with its connective tissue from 8 to 17 weeks of development. Collagen fibers were arranged in septa from the submucosa to the skin through the muscle. These septa were positive for type I collagen and presented elastic fibers. Fibrous septa that were positive for type III collagen were arranged from the lateral side of the muscle to the skin. Conclusions: The intimate relationship between buccinator muscle fibers and cheek connective tissue may explain the complex functions of this muscle.
Development of the Interosseous Muscles of the Human Hand: Morphological and Functional Aspects of the Terminal Insertion
(Cells, tissues, organs, 2024) Maldonado Bautista, Estela; Martínez Sanz, Elena; Catón Vázquez, Francisco Javier; Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Naredo, Esperanza; Murillo González, Jorge Alfonso; Mérida Velasco, José Ramón
Introduction: To date, there have been no studies conducted on the development of interosseous muscles (IO) in the human hand. This study aimed to investigate the development of these muscles in order to clarify their terminal insertions and their relationship with the metacarpophalangeal joints. Methods: Serial sections of 25 human specimens (9 embryos and 16 fetuses) between the 7th and 14th week of development, sourced from the Collection of the Department of Anatomy and Embryology at UCM Faculty of Medicine, were analysed bilaterally using a conventional optical microscope. Results: Our findings revealed that, during the 7th week of development, the metacarpophalangeal interzone mesenchyme extended into the extensor apparatus of the fingers. Furthermore, we observed that the joint capsule and the tendon of the IO derive from the articular interzone mesenchyme. By the end of the 7th week, corresponding to Carnegie stage 21, the myotendinous junction appeared, initiating cavitation of the metacarpophalangeal joint. During the fetal period, the terminal insertions of the IO were identified: both the dorsal interosseous (DI) and palmar interosseous (PI) muscles insert into the metacarpophalangeal joint capsule and establish a connection with the volar plate located at the base of the proximal phalanx and the extensor apparatus. Some muscle fibres also attach to the joint capsule at the level of the proximal synovial cul-de-sac. The functional implications of these findings are discussed within this work. Conclusion: This study provides the first detailed description of the development of the interosseous muscles in the human hand.
Functional hypothesis of the juxtaoral organ: Role of collagen types I and III
(Oral Diseases, 2021) Mérida García, Antonio José; Murillo González, Jorge Alfonso; Martínez Sanz, Elena; Catón Vázquez, Francisco Javier; Arráez Aybar, Luis Alfonso; Martín Cruces, José; Cobo, Teresa; Vega, José Antonio; Mérida Velasco, José Ramón
Project number: 165
Desarrollo de un sistema interactivo para el estudio de la órbita y su contenido: anatomía macroscópica
(2023) Asensio, Carmen; Arráez Aybar, Luis Alfonso; Catón Vázquez, Francisco Javier; García Serradilla, Moisés; García Gómez, Susana; García De Pereda Notario, Carlos Miguel; Maldonado Bautista, Estela; Martínez Sanz, Elena; Mérida Velasco, José Ramón; Murillo Barrio, Jaime; Murillo González, Jorge Alfonso; Naredo Sánchez, Esperanza; Paradas Lara, Irene; Virto Ruiz, Leire
En este proyecto se ha desarrollado un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de la anatomía macroscópica de la órbita y su contenido por medio de preparaciones anatómicas. Se pretende facilitar el aprendizaje de forma autónoma en español e inglés y, la autoevaluación sobre los conocimientos adquiridos.
Does Education about Death and Dying decrease stress generated in the dissection room?
(International Journal of Morphology, 2020) González Pinilla, Juan Ambrosio; Ruiz Gallego-Largo, Trinidad; Barrio Asensio, María Del Carmen; Catón Vázquez, Francisco Javier; Martínez Sanz, Elena; Murillo González, Jorge Alfonso
Positive effects on reducing students’ stress have been reported across numerous university settings when anatomy preparatory seminars have been provided. To date, this type of preparation for coping with cadaver dissection has not been studied in Spanish universities. The aim of this study is to evaluate how first-year Spanish medical students face the dissecting room and whether previous preparation about death and dying reduces the stress generated. We performed an interventional study with students who received preparatory classes before the dissection practices (Experimental Group, EG) and with students who did not (Control Group, CG). Sociodemographic data and a self-assessment on stress symptoms were collected through a questionnaire completed before and after the dissection practices. No differences were found in the self-report of symptoms of stress among students who consider themselves religious or not, or between students who had a family member in the healthcare environment or not. However, in the EG, the students who had ample experience with terminally ill patients or death reported fewer stress symptoms. Unexpectedly, the number of self- reported stress symptoms after the dissection practice was higher in EG students. In conclusion the stress levels of first-year Spanish medical students not only did not improve after receiving preparatory classes about death and dying and discussion groups, but it gets worse. We found a relationship between student stress measured and experience with terminally ill patients or death. Additional studies are needed to identify the most suitable preparation for Spanish medical students.
Connections between the internal and the external capsules and the globus pallidus in the sheep: A dichromate stain X‐ray microtomographic study
(Anatomia Histologia Embryologia, 2020) Murillo González, Jorge Alfonso; Notario, Belen; Maldonado Bautista, Estela; Martínez Sanz, Elena; Barrio Asensio, María Del Carmen; Herrera Lara, Manuel Eugenio
Sheep are recognized as useful species for translational neurodegeneration research, in particular for the study of Huntington disease. There is a lack of information regarding the detailed anatomy and connections of the basal ganglia of sheep, in normal myeloarchitectonics and in tract-tracing studies. In this work, the organization of the corticostriatal projections at the level of the putamen and globus pallidus (GP) are explored. For the first time, the myeloarchitectonic pattern of connections between the internal (IC) and the external (EC) capsules with the GP have been investigated in the sheep. Formaldehyde-fixed blocks of the striatum were treated with a metallic stain containing potassium dichromate and visualized using micro-CT (µ-CT). The trivalent chromium (Cr3+), attached to myelin phospholipids, imparts a differential contrast to the grey and white matter compartments, which allows the visualization of myelinated fascicles in µ-CT images. The fascicles were classified according to their topographical location in dorsal supreme fascicles (X, Y, apex) arising from the IC and EC; pre-commissurally, basal fascicles connecting the ventral part of the EC with the lateral zone of the ventral pallidum (VP) and, post-commissurally, superior (Z1 ), middle (Z2 ) and lower (Z3 ) fascicles, connecting at different levels the EC with the GP. The results suggest that the presumptive cortical efferent and afferent fibres to the pallidum could be organized according to a dorsal to ventrolateral topography in the sheep, similar to that seen in other mammals. The proposed methodology has the potential to delineate the myeloarchitectonic patterns of nervous systems and tracts.
Prevalence of retromolar foramen in nineteenth century Spanish population
(Odontology, 2022) Cury Carneiro, Mailon; Fischer Rubira,Cássia Maria; Martínez Sanz, Elena; Arráez Aybar, Luis Alfonso; Murillo González, Jorge Alfonso
Among the non-metrical variants of the mandible that have been proven to be a key issue for dental practitioners, the retromolar foramen constitutes one of the most controversial details regarding its prevalence and associated variables. Thus, this study evaluated the prevalence of the retromolar foramen and the variables associated with its presence in a large Spanish collection of human dry mandibles from the nineteenth century. Six hundred Spanish human dry mandibles (1200 sides) belonging to an osteology collection were examined. The presence of teeth, the presence or absence of retromolar foramen, as well as its side, diameter, number, and location were evaluated. Descriptive analysis and analysis of the associations between the variables were performed. The retromolar foramen was observed in 184 mandibles (31%) and was predominantly present unilaterally (60.8%). Most mandibles (54.9%) had a single foramen. The most common location was the retromolar trigone region (84%). On analysis of the association of variables, it was observed a strong association (p < 0.001) between the presence or absence of the foramen and the presence of teeth. Moreover, a significant association was also found between sex vs. presence of teeth (p = 0.033), sex vs. presentation side of the foramen (p = 0.028), sex vs. number of foramina found (p = 0.004), and diameter vs. number of foramina found (p < 0.001). This study reveals that the retromolar foramen showed a high prevalence of 31% in nineteenth century Spaniards and was located primarily in the retromolar trigone, suggesting that dentists should be aware of and consider the relevant findings of this study.
Project number: 419
Tomando medidas ante la COVID-19: Virtualización de las prácticas de Aparato Locomotor en las asignaturas que imparte el Departamento de Anatomía y Embriología en las titulaciones de Medicina, Fisioterapia, Podología y Terapia Ocupacional
(2022) Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Catón Vázquez, Francisco Javier; Cuadra Blanco, Crótida De La; García Gómez, Susana; Maldonado Bautista, Estela; Martínez Sanz, Elena; Mérida Velasco, José Ramón; Murillo González, Jorge Alfonso; Quirós Terrón, Luis; Sanz Casado, José Vicente
Desarrollo de un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de las prácticas del Aparato Locomotor, que pudiera ser utilizado por los alumnos de Grado de Fisioterapia, Medicina, Podología y Terapia Ocupacional, titulaciones en las que el Aparato Locomotor tiene una importante presencia en sus temarios de prácticas.
Project number: 79
Programación infográfica para la representación de los huesos y articulaciones del miembro inferior
(2021) Martínez Sanz, Elena; Murillo González, Jorge Alfonso; Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Herrera Lara, Manuel Eugenio; Cabrera Parra, Walter; Dorado Fernández, Enrique; Maldonado Bautista, Estela; Mérida Velasco, José Ramón; Catón Vázquez, Francisco Javier; Cuadra Blanco, Crótida De La; García Gómez, Susana; Becerro De Bengoa Vallejo, Ricardo
Desarrollo de una infografía con los huesos y articulaciones del miembro inferior para mejorar el proceso de enseñanza-aprendizaje en la docencia de la anatomía topográfica de estas estructuras a través del campus virtual (Grados de CC. de la Salud).