Person:
Cuadra Blanco, Crótida De La

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First Name
Crótida De La
Last Name
Cuadra Blanco
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Anatomía y Embriología
Area
Anatomía y Embriología Humana
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Now showing 1 - 10 of 12
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    Initial stages of development of the submandibular gland (human embryos at 5.5–8 weeks of development)
    (Journal of Anatomy, 2019) Quirós Terrón, Luis; Arráez Aybar, Luis Alfonso; Murillo González, Jorge Alfonso; Cuadra Blanco, Crótida De La; Martínez Álvarez, María Concepción; Sanz Casado, José Vicente; Mérida Velasco, José Ramón
    The aim of this study was to determine the main stages of submandibular salivary gland development during the embryonic period in humans. In addition, we studied submandibular salivary gland development in rats on embryonic days 14-16 and expression in the submandibular salivary gland region with the monoclonal antibody HNK-1. Serial sections from 25 human embryos with a greatest length ranging from 10 to 31 mm (Carnegie stages 16-23; weeks 5.5-8 of development) and Wistar rats of embryonic days (E) 14-16 were analysed with light microscopy. Five stages of submandibular salivary gland development were identified. The prospective stage (1), between weeks 5.5 and early week 6, is characterized by a thickening of the epithelium of the medial paralingual groove in the floor of the mouth corresponding to the primordium of the submandibular salivary gland parenchyma. At this stage, the primordium of the parasympathetic ganglion lies below the lingual nerve. The primordium of the submandibular salivary gland parenchyma is observed in rats on E14 in the medial paralingual groove with mesenchymal cells, underlying the lingual nerve. These cells are HNK-1-positive, corresponding to the primordium of the parasympathetic ganglion. The bud stage (2), at the end of week 6 in humans and on E15 in rats, is characterized by the proliferation and invagination of the epithelial condensation, surrounded by an important condensation of the mesenchyme. The pseudoglandular stage (3) at week 6.5 is characterized by the beginning of the formation of lobes in the condensed mesenchyme. The canalicular stage (4), between week 7 and 7.5, is characterized by the appearance of a lumen in the proximal part of the submandibular duct. The innervation stage (5) occurs during week 8, with the innervation of the submandibular and interlobular ducts. Nervous branches arriving from the parasympathetic ganglion innervate the glandular parenchyma. Numerous blood vessels are observed nearby. Our results suggest that submandibular salivary gland development requires interactions among epithelium, mesenchyme, parasympathetic ganglion and blood vessels.
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    Physicians' viewpoints on faculty anatomists and dissection of human bodies in the undergraduate medical studies
    (Annals of Anatomy, 2021) Arráez Aybar, Luis Alfonso; García Mata, Ricardo; Murillo González, Jorge Alfonso; Cuadra Blanco, Crótida De La; Gómez Martínez, Ana María; Bueno López, José Luis; Wojciech Pawlina, MD
    Background: Studies abound regarding the views of faculty anatomists and medical students on the importance of anatomy and the dissection of human bodies, but very little is known about the views of practicing physicians. Methods: A survey was distributed among physicians and surgeons practicing in Spain in order to find out their views on the practice and consequences of human dissection by undergraduate students of medicine. The most relevant definition to qualify faculty anatomists of medical schools was also requested. Responses were repeatedly clustered into characteristic subgroups for analysis. Results: In total, 536 physicians and surgeons belonging to 36 different specialties in seven Spanish hospitals responded to the survey. The results highlighted two main facts. Firstly, faculty anatomists were perceived as teachers, above any other professional identity (namely: physician, biologist or scientist); nonetheless, the ascription of identities varied between specialties (p=0.009); and it also depended on whether the respondents had dissected in their undergraduate degree (p=0.03) and on the respondent's gender (p=0.03). Secondly, physicians and surgeons confirmed that dissecting human cadavers serves the undergraduate student not only for acquiring anatomical knowledge, but also essential skills and attitudes, including professionalism. Conclusions: The results strongly suggest that dissection practice should be reinforced and enriched in undergraduate medical school. As this is important in itself, the results of the study could also help with the development of strategies to alleviate the current shortage of adequately trained anatomists for medical degrees.
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    Project number: 144
    Elaboración de modelos anatómicos y embriológicos mediante la impresión 3D
    (2016) Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Cabrera Parra, Walter; Cuadra Blanco, Crótida De La; Río Sevilla, Aurora Del; García Gómez, Susana; Herrera Lara, Manuel Eugenio; Maestro De Las Casas, María Del Carmen; Martínez Álvarez, María Concepción; Mérida Velasco, José Ramón; Murillo González, Jorge Alfonso; Naredo Sánchez, Esperanza; Quirós Terrón, Luis; Pérez De Miguelsanz, María Juliana
    La impresión 3D es un enfoque innovador en la docencia anatómica que puede proporcionar a los alumnos un material didáctico casi idéntico a la pieza embalsamada mitigando muchas de las múltiples controversias existentes en torno a la Disección
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    Anatomical relationships of the cleidoatlanticus muscle: Interpretation about its origin
    (Anatomical Science International, 2009) Rodríguez Vázquez, José Francisco; Mérida Velasco, José Ramón; Sanz Casado, José Vicente; Verdugo López, Samuel; Cuadra Blanco, Crótida De La
    An unusual muscular variation, the cleidoatlanticus muscle, was observed on the right-hand side of the lateral cervical region. The upper third of the muscle was concealed by the sternocleidomastoid muscle. There was a loop of nerves surrounding the muscle, formed by an anastomosis between the transverse cervical nerve and the greater auricular nerve. A fine vascular-nervous pedicle (formed by a small branch from the transverse cervical artery and by a branch from the medial supraclavicular nerve) entered the deep surface of the muscle at the junction of its middle and lower thirds. Taking into account the relationships that presented with the superficial branches of the cervical plexus, we consider that the cleidoatlanticus muscle is derived from the sternocleidomastoid muscle.
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    Development of the long head of the biceps brachial tendon: A possible explanation of the anatomical variations
    (Annals of Anatomy, 2018) Minuesa-Asensio, Alvaro; Murillo González, Jorge Alfonso; Cuadra Blanco, Crótida De La; Arráez Aybar, Luis Alfonso; Herrera Lara, Manuel Eugenio; Mérida Velasco, José Ramón
    The anatomical variations of the proximal portion of the long head of the biceps brachii tendon (LHBT) are rarely observed in clinical practice. However, an increase in the rate of shoulder arthroscopic surgery has led to an increase in the observation of anatomical variations of this region. The aim of this work was to analyze the development of the LHBT in 23 human embryos ranging from the 6th to 8th weeks of development. The LHBT develops from the glenohumeral interzonal mesenchyme in the 6th week. By week 7, the myotendinous junction of the LHBT develops. The anlage of the LHBT is separated from that of the glenohumeral capsule during week 8. Our results suggest that the most important period for the LHBT development occurs between the 6th and 8th weeks of embryonic development. Alterations during this critical period may cause anatomical variations of the LHBT. An additional case report from our own experience is provided as Supplementary material.
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    Development of the Platysma Muscle and the Superficial Musculoaponeurotic System (Human Specimens at 8–17 Weeks of Development)
    (Scientific World Journal, 2013) Cuadra Blanco, Crótida De La; Peces Peña, María Dolores; Carvallo de Moraes, L. O.; Herrera Lara, Manuel Eugenio; Mérida Velasco, José Ramón
    There is controversy regarding the description of the different regions of the face of the superficial musculoaponeurotic system (SMAS) and its relationship with the superficial mimetic muscles. The purpose of this study is to analyze the development of the platysma muscle and the SMAS in human specimens at 8–17 weeks of development using an optical microscope. Furthermore, we propose to study the relationship of the anlage of the SMAS and the neighbouring superficial mimetic muscles. The facial musculature derives from the mesenchyme of the second arch and migrates towards the different regions of the face while forming premuscular laminae. During the 8th week of development, the cervical, infraorbital, mandibular, and temporal laminae are observed to be on the same plane. The platysma muscle derives from the cervical lamina and its mandibular extension enclosing the lower part of the parotid region and the cheek, while the SMAS derives from the upper region. During the period of development analyzed in this study, we have observed no continuity between the anlage of the SMAS and that of the superficial layer of the temporal fascia and the zygomaticus major muscle. Nor have we observed any structure similar to the SMAS in the labial region.
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    Development of the Human Biceps Brachii Tendon and Coracoglenoid Ligament (7th-12th Week of Development)
    (Cells Tissues Organs, 2017) Cuadra Blanco, Crótida De La; Arráez Aybar, Luis Alfonso; Murillo González, Jorge Alfonso; Herrera Lara, Manuel Eugenio; Mérida Velasco, José Ramón
    The goal of this study is to clarify the development of the long head of the biceps brachii tendon (LHBT) and to verify the existence and development of the coracoglenoid ligament. Histological preparations of 22 human embryos (7-8 weeks of development) and 43 human fetuses (9-12 weeks of development) were studied bilaterally using a conventional optical microscope. The articular interzone gives rise to the LHBT, glenoid labrum, and articular capsule. During the fetal period, it was observed that in 50 cases (58%), the LHBT originated from both the glenoid labrum and the scapula, while in 36 cases (42%), it originated only from the glenoid labrum. The coracoglenoid ligament, first described by Sappey in 1867, is a constant structure that originates at the base of the coracoid process and projects toward the glenoid labrum zone, which is related to the origin of the LHBT. The coracoglenoid ligament was more easily identifiable in the 36 cases in which the LHBT originated only from the glenoid labrum. We suggest that the coracoglenoid ligament is a constant anatomical structure, is not derived from the articular interzone unlike the LHBT, and contributes to the fixation of the glenoid labrum in the scapula in cases in which the LHBT originated only from the glenoid labrum. We postulate that, when the LHBT is fixed only at the glenoid labrum, alterations in the coracoglenoid ligament could lead to a less sufficient attachment of the glenoid labrum to the scapula which could predispose to a superior labral lesion.
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    Project number: 419
    Tomando medidas ante la COVID-19: Virtualización de las prácticas de Aparato Locomotor en las asignaturas que imparte el Departamento de Anatomía y Embriología en las titulaciones de Medicina, Fisioterapia, Podología y Terapia Ocupacional
    (2022) Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Catón Vázquez, Francisco Javier; Cuadra Blanco, Crótida De La; García Gómez, Susana; Maldonado Bautista, Estela; Martínez Sanz, Elena; Mérida Velasco, José Ramón; Murillo González, Jorge Alfonso; Quirós Terrón, Luis; Sanz Casado, José Vicente
    Desarrollo de un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de las prácticas del Aparato Locomotor, que pudiera ser utilizado por los alumnos de Grado de Fisioterapia, Medicina, Podología y Terapia Ocupacional, titulaciones en las que el Aparato Locomotor tiene una importante presencia en sus temarios de prácticas.
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    Physicians' viewpoints on faculty anatomists and dissection of human bodies in the undergraduate medical studies
    (Annals of Anatomy, 2021) Arráez Aybar, Luis Alfonso; García Mata, Ricardo; Murillo González, Jorge Alfonso; Cuadra Blanco, Crótida De La; Gómez Martínez, Ana María; Bueno López, José Luis
    Background: Studies abound regarding the views of faculty anatomists and medical students on the importance of anatomy and the dissection of human bodies, but very little is known about the views of practicing physicians. Methods: A survey was distributed among physicians and surgeons practicing in Spain in order to find out their views on the practice and consequences of human dissection by undergraduate students of medicine. The most relevant definition to qualify faculty anatomists of medical schools was also requested. Responses were repeatedly clustered into characteristic subgroups for analysis. Results: In total, 536 physicians and surgeons belonging to 36 different specialties in seven Spanish hospitals responded to the survey. The results highlighted two main facts. Firstly, faculty anatomists were perceived as teachers, above any other professional identity (namely: physician, biologist or scientist); nonetheless, the ascription of identities varied between specialties (p = 0.009); and it also depended on whether the respondents had dissected in their undergraduate degree (p = 0.03) and on the respondent’s gender (p = 0.03). Secondly, physicians and surgeons confirmed that dissecting human cadavers serves the undergraduate student not only for acquiring anatomical knowledge, but also essential skills and attitudes, including professionalism. Conclusions: The results strongly suggest that dissection practice should be reinforced and enriched in undergraduate medical school. As this is important in itself, the results of the study could also help with the development of strategies to alleviate the current shortage of adequately trained anatomists for medical degrees.
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    Project number: 79
    Programación infográfica para la representación de los huesos y articulaciones del miembro inferior
    (2021) Martínez Sanz, Elena; Murillo González, Jorge Alfonso; Arráez Aybar, Luis Alfonso; Barrio Asensio, María Del Carmen; Herrera Lara, Manuel Eugenio; Cabrera Parra, Walter; Dorado Fernández, Enrique; Maldonado Bautista, Estela; Mérida Velasco, José Ramón; Catón Vázquez, Francisco Javier; Cuadra Blanco, Crótida De La; García Gómez, Susana; Becerro De Bengoa Vallejo, Ricardo
    Desarrollo de una infografía con los huesos y articulaciones del miembro inferior para mejorar el proceso de enseñanza-aprendizaje en la docencia de la anatomía topográfica de estas estructuras a través del campus virtual (Grados de CC. de la Salud).