Solving industrial design problems by using COMSOL Multiphysics with MATLAB

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COMSOL Multiphysics is a very efficient tool for modeling numerically complex devices. In particular, this software can be used during the industrial design processes involving optimization problems.One interesting characteristic of COMSOL Multiphysics is the possibility of incorporating the created model into a MATLAB script code. This allows the MATLAB script to automatically change some considered model parameters, such as geometrical shapes, physical characteristics, etc. Thus, any optimization algorithm compatible with MATLAB script can solve an optimization problem involving a COMSOL Multiphysics model. During this minicourse, first we will detail the basic steps to create and solve industrial design problems by coupling COMSOL Multiphysics with MATLAB. Then, we will illustrate the presented methodology by considering the optimization of a fast hydrodynamic focusing microfluidic mixer for protein folding.
Benjamin Ivorra, Juana Redondo, Juan Santiago, Pilar Ortigosa, and Angel Ramos. Two- and three-dimensional modeling and optimization applied to the design of a fast hydrodynamic focusing microfluidic mixer for protein folding. Physics of Fluids, 25, 032001, 2013. David E. Hertzog, Benjamin Ivorra, Bijan Mohammadi, Olgica Bakajin, Juan G. Santiago. Optimization of a Fast Microfluidic Mixer for Studying Protein Folding Kinetics. Analytical chemistry, 78(13), 4299-4306, 2006. Benjamin Ivorra, David E. Hertzog, Bijan Mohammadi, Juan G. Santiago. Semi-deterministic and genetic algorithms for global optimization of microfluidic protein-folding devices. International Journal for Numerical Methods in Engineering , 66(2), 319-333, 2006