Neutron fibres and possible applications to NCT

Thumbnail Image
Full text at PDC
Publication Date
Advisors (or tutors)
Journal Title
Journal ISSN
Volume Title
Pergamon-Elsevier Science Ldt
Google Scholar
Research Projects
Organizational Units
Journal Issue
We summarize previous researches regarding neutron guides of small transverse cross-section (neutron fibres), smaller than those of the standard hollow guides and collimators employed currently. Those studies may not be widely known in the neutron capture therapy (NCT) community, but they may be interesting for it. Such neutron fibres could allow to deliver and concentrate neutron beams selectively in regions of size smaller than 1 mm. We present new estimates and point out and discuss some new possible specific applications of those neutron fibres, which would not replace standard NCT but could supplement it. Thus, we entertain the possibility that neutron fibres could be useful for additional therapies (in typical NCT durations) of: (i) rather small tumours, (ii) thin borders of tumours. The use of these neutron fibres could reduce the undesirable delivery of radiation to healthy tissue around regions with malignant tissue.
© 2004 Elsevier Ltd. World Congress on Neutron Capture Therapy (11º. 2004. Boston, EE.UU.). Both authors acknowledge the financial support of Ministerio de Ciencia y Tecnología, Spain: R.F. A.-E. through Proyecto FPA2000-0956, while M.L.C. through Proyecto TIC2002-1846. We are grateful to Dr. J.F. Crawford for interesting correspondence, Mrs. Reiko Matsuoka for providing kindly information about the activities of the NCT community and to the referees for comments and criticism. R.F. A.-E. is Associate Member of Instituto de Biocomp. y Física de Sist. Compl., Universidad de Zaragoza, Zaragoza, Spain.
1. Alvarez-Estrada, R.F., Calvo, M.L., 1984. J. Phys. D. Appl. Phys. 17, 475. 2. Calvo, M.L., 2000. J. Phys. D. Appl. Phys. 33, 1666. 3. Calvo, M.L., 2001. Neutron capture therapy, Investigacion y Ciencia (Spanish Edition of Scientific American). Section Sci. Soc. 298, 35. 4. Calvo, M.L., Alvarez-Estrada, R.F., 1986. J. Phys. D. Appl. Phys. 19, 957. 5. Calvo, M.L., Alvarez-Estrada, R.F., 2002. Neutron optics, neutron waveguides and applications. In: Guenther, H.G. (Ed.), International Trends in Applied Optics. Vol. V. International Commission for Optics, SPIE (The International 6. Society for Optical Engineering), Bellingham, USA. 7. Chen, H., Downing, R.G., Mildner, D.F.R., Gibson, W.M., Kumakhov, M.A., Ponomarev, I.Yu., Gubarev, M.V., 1992. Nature 357, 391. 8. Crist, J., Springer, T., 1962. Nukleonik 4, 23. 9. Hatanaka, H., 1991. Boron-neutron capture therapy for tumors. In: Karim/Laws (Eds.), Glioma. Springer, Berlin, Germany. 10. Kumakhov, M.A., Sharov, V.A., 1992. Nature 357, 390. 11. Maier-Leibnitz, H., Springer, T., 1963. J. Nucl. Energy A/B17, 217. 12. Proceedings of the Ninth International Symposium on NCT for Cancer, 2000, October 2–6, Osaka, Japan. 13. Rohwedder, B., 2002. Phys. Rev. A 65, 043619. 14. Sauerwein, W., Moss, R., Wittig, A., (Eds.) 2002. Research and Development in NCT. Monduzzi Editore, Bologna, Italy.