RT Journal Article
T1 Do sex and gender aspects influence non-adherence to secondary prevention measures after myocardial infarction?
A1 Moreno Muñoz, Guillermo
A1 Vicent, Lourdes
A1 Rosillo, Nicolás
A1 Delgado Jiménez, Juan Francisco
A1 Pacheco del Cerro, Enrique
A1 Bueno Zamora, Héctor José
AB Objective: This study aimed to determine the prevalence of non-adherence to preventive interventions, its clinical consequences, and factors associated with non-adherence to secondary prevention measures, with a special emphasis on sex and gender.Methods: Prospective observational study of patients hospitalized for acute myocardial infarction (AMI) in whom an evaluation of adherence to medication, Mediterranean diet, physical activity, and cardiac rehabilitation was performed after 6 and 12 months, with systematic assessment of predictors including patient-, disease-, psychological-, social-, and gender-related factors using self-administered questionnaires.Results: Of 503 patients included, 101 (20,1%) were females. At one year, 85% of patients did not adhere to at least one of the recommendations with no differences between females and males. However, two factors more frequent in females, caregiver burden (adjusted OR, 1.45; 95%CI, 1.08-1.94) and depressive symptoms (adjusted OR, 1.40; 95%CI, 1.03-1.92) predicted non-adherence to all measures together. Chronic kidney disease (aOR, 3.24; 95%CI, 1.02-10.48) and being female (aOR, 2.21; 95%CI, 1.18-4.13) were associated with non-adherence to the Mediterranean diet; diabetes with organ damage (aOR, 12.06; 95%CI, 1.93-7.69) and older age (aOR, 0.96 per year; 95%CI, 0.93-0.99), among others, with physical activity; and higher body mass index with cardiac rehabilitation participation (aOR, 1.07; 95%CI, 1.002-1.14) and completion (aOR, 1.14; 95%CI, 1.03-1.26).Conclusion: Adherence to all secondary prevention measures after AMI remains very low and is associated with several gender-related factors. Multidisciplinary intervention strategies targeting the most vulnerable patient groups, such as females or patients with diabetes, obesity, chronic kidney disease, or depression, are warranted.
PB Elsevier
SN 2666-6677
YR 2024
FD 2024
LK https://hdl.handle.net/20.500.14352/108723
UL https://hdl.handle.net/20.500.14352/108723
LA eng
NO Moreno G, Vicent L, Rosillo N, Delgado J, Cerro EPD, Bueno H. Do sex and gender aspects influence non-adherence to secondary prevention measures after myocardial infarction? Am J Prev Cardiol. 2024 Aug 3;19:100713. doi: 10.1016/j.ajpc.2024.100713.
NO SEC Project for Clinical Research in Cardiology 2019 to the work “Predictors of non-compliance with secondary prevention measures in myocardial infarction”.
NO Sociedad Española de Cardiología
DS Docta Complutense
RD 5 abr 2025