TY  - JOUR
AU  - Tirado Vélez, Jose Manuel
AU  - Carreño, David
AU  - Sevillano Fernández, David
AU  - Alou Cervera, Luis
AU  - Yuste, José
AU  - de la Campa, Adela G.
PY  - 2021
DO  - 10.3390/antibiotics10050573
SN  - 2079-6382
UR  - https://hdl.handle.net/20.500.14352/7123
T2  - Antibiotics
AB  - Antibiotic resistance in Streptococcus pneumoniae has increased worldwide, making fluoroquinolones an alternative therapeutic option. Fluoroquinolones inhibit the type II DNA topoisomerases (topoisomerase IV and gyrase). In this study we have...
LA  - eng
M2  - 573
PB  - MPDI
KW  - Streptococcus pneumoniae
KW  - DNA topoisomerase I inhibitor
KW  - seconeolitsine
KW  - resistance
KW  - invasive pneumococcal disease
TI  - Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains
TY  - journal article
VL  - 10
ER  -