TY  - JOUR
AU  - García Esteban, María Teresa
AU  - Blázquez, María Amparo
AU  - Ferrándiz, María José
AU  - Sanz, María Jesús
AU  - Silva Martín, Noella
AU  - Hermoso, Juan Antonio
AU  - G. de la Campa, Adela
PY  - 2011
DO  - 10.1074/jbc.M110.148148
SN  - 0021-9258
UR  - https://hdl.handle.net/20.500.14352/125406
T2  - The Journal of Biological Chemistry
AB  - Streptococcus pneumoniae has two type II DNA-topoisomerases (DNA-gyrase and DNA topoisomerase IV) and a single type I enzyme (DNA-topoisomerase I, TopA), as demonstrated here. Although fluoroquinolones target type II enzymes, antibiotics efficiently...
LA  - eng
M2  - 6402
PB  - Elsevier
KW  - Antibiotics
KW  - DNA Topoisomerase
KW  - DNA Topology
KW  - Drug Resistance
KW  - Protein-DNA Interaction
TI  - New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae
TY  - journal article
VL  - 286
ER  -