RT Journal Article
T1 Novel ion-doped mesoporous glasses for bone tissue engineering: Study of their structural characteristics influenced by the presence of phosphorous oxide
A1 Philippart, Anahí
A1 Gómez Cerezo, María Natividad
A1 Arcos Navarrete, Daniel
A1 Salinas Sánchez, Antonio J.
A1 Boccardi, Elena
A1 Vallet Regí, María Dulce Nombre
A1 Boccaccini, A. R.
AB Ion-doped binary SiO2-CaO and ternary SiO2-CaO-P2O5 mesoporous bioactive glasses were synthesized and characterized to evaluate the influence of P2O5 in the glass network structure. Strontium, copper and cobalt oxides in a proportion of 0.8 mol% were selected as dopants because the osteogenic and angiogenic properties reported for these elements. Although the four glass compositions investigated presented analogous textural properties, TEM analysis revealed that the structure of those containing P2O5 exhibited an increased ordered mesoporosity. Furthermore, 29Si NMR revealed that the incorporation of P2O5 increased the network connectivity and that this compound captured the Sr2 +, Cu2 + and Co2 + ions preventing them to behave as modifiers of the silica network. In addition, 31P NMR results revealed that the nature of the cation directly influences the characteristics of the phosphate clusters. In this study, we have proven that phosphorous oxide entraps doping-metallic ions, granting these glasses with a greater mesopores order.
PB Elsevier
SN 0022-3093
YR 2017
FD 2017-01-01
LK https://hdl.handle.net/20.500.14352/17681
UL https://hdl.handle.net/20.500.14352/17681
LA eng
NO RESEARCHER ID M-3378-2014 (María Vallet Regí)ORCID 0000-0002-6104-4889 (María Vallet Regí)RESEARCHER ID M-3316-2014 (Antonio Salinas Sánchez)ORCID 0000-0002-8408-3389 (Antonio Salinas Sánchez)RESEARCHER ID L-6167-2014 (Daniel Arcos Navarrete)ORCID 0000-0002-5367-7272 (Daniel Arcos Navarrete)
NO Unión Europea. H2020
NO Unión Europea. FP7
NO Ministerio de Economía y Competitividad (MINECO)
NO Agening Network of Excellence
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 30 abr 2024