TY - JOUR AU - Rabuffetti, Marco AU - Cannazza, Pietro AU - Contente, Martina Letizia AU - Pinto, Andrea AU - Romano, Diego AU - Hoyos Vidal, María Pilar AU - Alcántara León, Andrés Rafael AU - Eberini, Ivano AU - Laurenzi, Tommaso AU - Gourlay, Louise AU - Di Pisa, Flavio AU - Molinari, Francesco AU - Molinari, Francesco AU - Elsevier PY - 2021 DO - 10.1016/j.bioorg.2021.104644 SN - 0045-2068 UR - https://hdl.handle.net/20.500.14352/96618 T2 - Bioorganic Chemistry AB - Benzil reductases are dehydrogenases preferentially active on aromatic 1,2-diketones, but the reasons for this peculiar substrate recognition have not yet been clarified. The benzil reductase (KRED1-Pglu) from the non conventional yeast Pichia... LA - eng M2 - 104644 PB - Elsevier KW - Biocatalysis, Ketoreductase, Pichia glucozyma, Enzymatic reduction, Crystal structure, In silico analysis TI - Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction TY - journal article VL - 108 ER -