%0 Journal Article
%A Cárdenas Escudero, J.
%A Cáceres, Jorge Omar
%A Navarro Villoslada, Fernando
%A Bellini, G.
%A Galán Madruga, D.
%A Cáceres, Jorge Omar
%T Determination of bioequivalence between generic and reference drugs using laser-induced breakdown spectroscopy
%D 2024
%U https://hdl.handle.net/20.500.14352/115750
%X In vitro bioequivalence studies are strictly limited to the comparison of dissolution performance to a reference drug. These studies are performed without considering the chemical similarity between the generic and reference drug formulations. This work has focused on developing a groundbreaking method based on the laser-induced breakdown spectroscopy (LIBS) technique for the in vitro bioequivalence determination of immediate-release solid oral dosage form generic drugs and as an alternative method for establishing the biowaiver of in vivo generic drug studies.
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