RT Journal Article T1 Development of the stapedius muscle and unilateral agenesia of the tendon of the stapedius muscle in a human fetus A1 Rodríguez Vázquez, José Francisco A1 Mérida Velasco, José Ramón A1 Verdugo López, Samuel AB The objective was to analyze the development of the stapedius muscle to understand an isolated unilateral absence of the tendon of the stapedius muscle in a human fetus. The study was made on 50 human embryos and fetuses aged 38 days to 17 weeks post-conception. The stapedius muscle was formed by two anlagen, one for the tendon, which derives from the internal segment of the interhyale and another for the belly, located in the second pharyngeal arch, medially to the facial nerve and near the interhyale. In the interhyale, two segments were observed forming an angle and delimited by the attachment of the belly of the stapedius muscle. The internal segment will form the tendon. The lateral segment of the interhyale was attached to the cranial end of the Reichert's cartilage (laterohyale), and normally it disappears at the beginning of the fetal period. The right unilateral agenesia of the tendon of the stapedius muscle, observed for the first time in a human fetus of 14 weeks post-conception development (PCd), was brought about by the lack of formation or the regression of the internal segment of the interhyale. It presented a belly of the stapedius muscle with an anomalous arrangement, and with a pseudo tendon originated by the persistence of the external segment of the interhyale. PB Wiley SN 1932-8494 YR 2010 FD 2010-01 LK https://hdl.handle.net/20.500.14352/97535 UL https://hdl.handle.net/20.500.14352/97535 LA eng NO Rodríguez-Vázquez JF, Mérida-Velasco JR, Verdugo-López S. Development of the stapedius muscle and unilateral agenesia of the tendon of the stapedius muscle in a human fetus. Anatomical Record (Hoboken). 2010 Jan;293(1):25-31. DS Docta Complutense RD 18 abr 2025