RT Journal Article
T1 Correlation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses
A1 Izquierdo Moreno, Jorge
A1 Illán de Paz, Marta
A1 Manso Díaz, Gabriel
A1 Villalba Orero, María
A1 López San Román, Francisco Javier
AB BackgroundAn accurate evaluation of the degree of sedation is mandatory to adjust the dosage of sedative drugs.ObjectivesTo determine the correlation between head height above the ground and ataxia degree in horses sedated with detomidine and the correlation existing between accelerometric variables and both parameters.Study designRetrospective study.MethodsTwelve horses were given 0.01 mg/kg of detomidine hydrochloride iv. Measured accelerometric parameters, with one accelerometer positioned between both sacral tuberosities, included speed, stride frequency and length, regularity, dorsoventral, longitudinal, mediolateral and total accelerometric activities, relative force index and dorsoventral, longitudinal and mediolateral parts of the accelerometric activities. Head height above the ground (cm) and subjective ataxia degree were also measured. Baseline values (−15 min) and values measured 5 and 15 min after the injection and then every 15 min for a period of 2 h were obtained.ResultsThere was a negative and strong correlation between head height above the ground and ataxia degree (Pearson r = −0.78, p < 0.001), particularly during the first 45 min. A significant correlation was found between head height above the ground and almost all accelerometric parameters. This correlation was very strong with stride frequency, regularity and dorsoventral and total accelerometric activities in both cases, but for ataxia, also with total accelerometric activity.Main limitationsExperimental conditions may not represent real clinical situations.ConclusionsStride frequency and regularity are the most reliable parameters to determine degree of sedation and are related to the sedation produced. Ataxia should not be considered a separate property of sedation and does not need to be assessed separately to the depth of sedation
PB Wiley
YR 2024
FD 2024-08-14
LK https://hdl.handle.net/20.500.14352/107854
UL https://hdl.handle.net/20.500.14352/107854
LA eng
NO Izquierdo-Moreno, J., de Paz, M. I., Manso-Díaz, G., Villalba-Orero, M., & López-Sanromán, J. (2024). Correlation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses. Equine veterinary journal, 10.1111/evj.14207. Advance online publication. https://doi.org/10.1111/evj.14207
DS Docta Complutense
RD 6 oct 2024