RT Journal Article
T1 Regenerative medicine: Hydrogels and mesoporous silica nanoparticles
A1 Pablos Lagartos, Jesús Luis
A1 Lozano Borregón, Daniel
A1 Manzano García, Miguel
A1 Vallet Regí, María Dulce Nombre
AB Hydrogels, that are crosslinked polymer networks, can absorb huge quantities of water and/or biological fluids. Their physical properties, such as elasticity and soft tissue, together with their biocompatibility and biodegradability, closely resemble living tissues. The versatility of hydrogels has fuelled their application in various fields, such as agriculture, biomaterials, the food industry, drug delivery, tissue engineering, and regenerative medicine. Their combination with nanoparticles, specifically with Mesoporous Silica Nanoparticles (MSNs), have elevated these composites to the next level, since MSNs could improve the hydrogel mechanical properties, their ability to encapsulate and controlled release great amounts of different therapeutic agents, and their responsiveness to a variety of external and internal stimuli. In this review, the main features of both MSNs and hydrogels are introduced, followed by the discussion of different hydrogels-MSNs structures and an overview of their use in different applications, such as drug delivery technologies and tissue engineering.
PB Elsevier
SN 2590-0064
YR 2024
FD 2024-12-21
LK https://hdl.handle.net/20.500.14352/111880
UL https://hdl.handle.net/20.500.14352/111880
LA eng
NO Jesús L. Pablos, Daniel Lozano, Miguel Manzano, María Vallet-Regí, Regenerative medicine: Hydrogels and mesoporous silica nanoparticles, Materials Today Bio, Volume 29, 2024, 101342, https://doi.org/10.1016/j.mtbio.2024.101342.
NO Ministerio de Ciencia e Innovación (España)
NO European Commission
DS Docta Complutense
RD 9 abr 2025