TY  - JOUR
AU  - Fernández Gómez-Chacón, Gerónimo Félix
AU  - Moraga Yébenes, Ana
AU  - Cuartero Desviat, María Isabel
AU  - García Culebras, Alicia
AU  - Peña Martínez, Carolina Belén
AU  - Pradillo Justo, Jesús Miguel
AU  - Lizasoaín Hernández, Ignacio
PY  - 2018
DO  - 10.1016/j.ymthe.2018.05.019
SN  - 1525-0016
UR  - https://hdl.handle.net/20.500.14352/95810
T2  - Molecular Therapy
AB  - Since Toll-like receptor 4 (TLR4) mediates brain damage after stroke, development of TLR4 antagonists is a promising therapeutic strategy for this disease. Our aim was to generate TLR4-blocking DNA aptamers to be used for stroke treatment. From a...
LA  - eng
M2  - 2047
PB  - Cell Press
KW  - SELEX
KW  - Aptamer
KW  - Infarction
KW  - Inflammation
KW  - Ischemia
KW  - Stroke
KW  - Therapy
KW  - TLR4
TI  - TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models
TY  - journal article
VL  - 26
ER  -