RT Book, Section
T1 Wire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteries
A1 Del Campo Milán, Lara
A1 Ferrer, Mercedes
AB Atherosclerosis is characterized by endothelial dysfunction and alterations in vascular reactivity, which can be investigated by wire myography. The method allows ex vivo monitoring of the transversal isometric tension developed by a vessel segment in response to different pathophysiological stimuli. Here we describe in detail how to use the wire myograph to evaluate endothelial function and vasoconstrictor or vasodilator properties of the vessel, as well as to identify and characterize different factors and molecular pathways that control vascular tone. We also describe how to use the wire myograph to analyze biomechanical and passive properties of vessels such as diameter and elasticity.
PB Springer Science+Business Media
SN 978-1-4939-2928-3
SN 978-1-4939-4935-9
SN 1064-3745
YR 2015
FD 2015
LK https://hdl.handle.net/20.500.14352/96572
UL https://hdl.handle.net/20.500.14352/96572
LA eng
NO Del Campo L, Ferrer M (2015) Wire Myography to Study Vascular Tone and Vascular Structure of Isolated Mouse Arteries. In: Andrés V, Dorado B (eds) Methods in Mouse Atherosclerosis. Springer New York, New York, NY, pp 255–276
NO Ministerio de Sanidad (España)
NO Comunidad de Madrid
NO Ministerio de Economía, Comercio y Empresa (España)
NO European Commission
DS Docta Complutense
RD 22 ene 2026