%0 Journal Article
%A Montes-Ares, Olga
%A Moya-Quiles, Rosa
%A Montes-Casado, María
%A Guerra Pérez, Natalia
%A Campillo, Juan Antonio
%A González, Consuelo
%A López-Bermejo, Antonio
%A Tamayo, Manuel
%A Majado, Juliana
%A Parrado, Antonio
%A Muro, Manuel
%A Marín, Luis
%A Alvarez-López, Rocio
%T Human leucocyte antigen-C in B chronic lymphocytic leukaemia
%D 2006
%@ 0007-1048
%U https://hdl.handle.net/20.500.14352/97986
%X This study aimed at characterising the distribution of human leucocyte antigen (HLA)-C alleles in a large group of patients with B chronic lymphocytic leukaemia from Southeastern Spain. Ninety-eight adult patients and 194 geographically and ethnically matched controls were studied. HLA-C was determined by polymerase chain reaction sequence-specific primers (PCR-SSP) and PCR-sequence-specific oligonucleotides (SSO) methods. The HLA-Cw*16 allele frequency was found to be significantly increased amongst patients compared with controls in our population (27·6% vs. 12·4%, P = 0·0012, Pc = 0·016). HLA-C dimorphism was also analysed but no association was found.
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