RT Journal Article
T1 Human leucocyte antigen-C in B chronic lymphocytic leukaemia
A1 Montes-Ares, Olga
A1 Moya-Quiles, Rosa
A1 Montes-Casado, María
A1 Guerra Pérez, Natalia
A1 Campillo, Juan Antonio
A1 González, Consuelo
A1 López-Bermejo, Antonio
A1 Tamayo, Manuel
A1 Majado, Juliana
A1 Parrado, Antonio
A1 Muro, Manuel
A1 Marín, Luis
A1 Alvarez-López, Rocio
AB This study aimed at characterising the distribution of human leucocyte antigen (HLA)-C alleles in a large group of patients with B chronic lymphocytic leukaemia from Southeastern Spain. Ninety-eight adult patients and 194 geographically and ethnically matched controls were studied. HLA-C was determined by polymerase chain reaction sequence-specific primers (PCR-SSP) and PCR-sequence-specific oligonucleotides (SSO) methods. The HLA-Cw*16 allele frequency was found to be significantly increased amongst patients compared with controls in our population (27·6% vs. 12·4%, P = 0·0012, Pc = 0·016). HLA-C dimorphism was also analysed but no association was found.
PB Wiley
SN 0007-1048
YR 2006
FD 2006
LK https://hdl.handle.net/20.500.14352/97986
UL https://hdl.handle.net/20.500.14352/97986
LA eng
NO Montes‐Ares, Olga, et al. «Human Leucocyte antigen‐C in B Chronic Lymphocytic Leukaemia». British Journal of Haematology, vol. 135, n.o 4, noviembre de 2006, pp. 517-19. https://doi.org/10.1111/j.1365-2141.2006.06334.x.
NO Ministerio de Sanidad y Consumo (España)
DS Docta Complutense
RD 7 abr 2025