%0 Journal Article %A Dosil, Sara %A Rodríguez-Galán, Ana %A Sánchez-Madrid, Francisco %A Fernández Messina, Lola María %T MicroRNAs in T Cell-Immunotherapy %D 2022 %U https://hdl.handle.net/20.500.14352/97239 %X MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and disease. Despite the rapidly growing body of evidence on the theranostic potential of restoring miRNA levels in pre-clinical models, the translation into clinics remains limited. Here, we review the current knowledge of miRNAs as T-cell targeting immunotherapeutic tools, and we offer an overview of the recent advances in miRNA delivery strategies, clinical trials and future perspectives in RNA interference technologies. %~