TY  - JOUR
AU  - Marqués, Patricia
AU  - Burillo Maldonado, Jesús
AU  - González Blanco, Carlos
AU  - Jiménez, Beatriz
AU  - García, Gema
AU  - García Aguilar, Ana
AU  - Iglesias Fortes, Sara
AU  - Lockwood, Ángela
AU  - Guillén, Carlos
AU  - Guillén Viejo, Carlos
PY  - 2024
DO  - 10.1038/s41598-024-63525-7
UR  - https://hdl.handle.net/20.500.14352/113706
T2  - Scientific Reports
AB  - Sirtuin1 (SIRT1) activity decreases the tuberous sclerosis complex 2 (TSC2) lysine acetylation status, inhibiting the mechanistic target of rapamycin complex 1 (mTORC1) signalling and concomitantly, activating autophagy. This study analyzes the role...
LA  - eng
KW  - TSC2
KW  - Acetylation
KW  - Lysosome
KW  - mTORC1
KW  - Mitophagy
KW  - Pancreatic β cells
TI  - Regulation of TSC2 lysosome translocation and mitochondrial turnover by TSC2 acetylation status
TY  - journal article
VL  - 14
ER  -