RT Journal Article T1 Sex differences in neuroimmunoendocrine communication. Involvement on longevity A1 Suárez González, Luz María A1 Díaz Del Cerro, Estefanía A1 Félix, Judith A1 González Sánchez, Mónica A1 Ceprián, Noemí A1 Guerra Pérez, Natalia A1 Garrido Novelle, Marta A1 Martínez De Toda Cabeza, Irene A1 Fuente Del Rey, María Mónica De La AB Endocrine, nervous, and immune systems work coordinately to maintain the global homeostasis of the organism. They show sex differences in their functions that, in turn, contribute to sex differences beyond reproductive function. Females display a better control of the energetic metabolism and improved neuroprotection and have more antioxidant defenses and a better inflammatory status than males, which is associated with a more robust immune response than that of males. These differences are present from the early stages of life, being more relevant in adulthood and influencing the aging trajectory in each sex and may contribute to the different life lifespan between sexes. PB Elsevier SN 0047-6374 YR 2023 FD 2023 LK https://hdl.handle.net/20.500.14352/88568 UL https://hdl.handle.net/20.500.14352/88568 LA eng NO Suarez LM, Diaz-Del Cerro E, Felix J, Gonzalez-Sanchez M, Ceprian N, Guerra-Perez N, Novelle MG, Martinez de Toda I, De la Fuente M. Sex differences in neuroimmunoendocrine communication. Involvement on longevity. Mech Ageing Dev. 2023 Apr;211:111798. NO Universidad Complutense de Madrid DS Docta Complutense RD 17 abr 2025