RT Journal Article T1 Charge transfer in DNA: effective Hamiltonian approaches A1 Maciá Barber, Enrique Alfonso AB Aperiodic order plays a very significant role in biology, as it determines most informative content of genomes. Amongst the various physical, chemical or biological phenomena that might be inferred from sequence correlations, charge transfer properties deserve particular attention. Indeed, the nature of DNA-mediated charge migration has been related to the understanding of damage recognition process, protein binding, or with the task of engineering biological processes (e.g. designing nanoscale sensing of genomic mutations), opening new challenges for emerging nanobiotechnologies. Nevertheless, the solution of Schrodinger's equation with a potential that is given by a one-dimensional array of the double-stranded DNA remains as a main open theme in solid state physics of biological macromolecules. In this contribution, I will shortly review several approaches introduced during the last few years in order to describe charge transfer migration in DNA in terms of tight-binding effective Hamiltonians. PB Oldenbourg Verlag SN 0044-2968 YR 2009 FD 2009 LK https://hdl.handle.net/20.500.14352/52100 UL https://hdl.handle.net/20.500.14352/52100 LA eng NO © Oldenbourg Verlag.This work has been supported by the Universidad Complutense de Madrid through project No. PR34/07- 15824-BSCH. NO Universidad Complutense de Madrid/Banco de Santander DS Docta Complutense RD 9 may 2025