RT Journal Article
T1 H2-Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration
A1 Gutiérrez-Sanz, Óscar
A1 Natale, Paolo
A1 Márquez, Ileana
A1 Marques, Marta C.
A1 Zacarias, Sonia
A1 Pita, Marcos
A1 Pereira, Inês A. C.
A1 López-Montero, Iván
A1 De Lacey, Antonio L.
A1 Vélez, Marisela
AB ATP, the molecule used by living organisms to supply energy to many different metabolic processes, is synthesized mostly by the ATPase synthase using a proton or sodium gradient generated across a lipid membrane. We present evidence that a modified electrode surface integrating a NiFeSe hydrogenase and a F1F0 -ATPase in a lipid membrane can couple the electrochemical oxidation of H2 to the synthesis of ATP. This electrode-assisted conversion of H2 gas into ATP could serve to generate this biochemical fuel locally when required in biomedical devices or enzymatic synthesis of valuable product.
PB Wiley-VCH Verlag GmbH & Co. KGaA.
SN 1433-7851
YR 2016
FD 2016
LK https://hdl.handle.net/20.500.14352/23740
UL https://hdl.handle.net/20.500.14352/23740
LA eng
NO The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (ERC grant agreement n° 338133)
NO Unión Europea. FP7
NO Ministerio de Economía y Competitividad (MINECO)
NO Fundação para a Ciência ê a Tecnologia
DS Docta Complutense
RD 7 abr 2025