RT Journal Article T1 A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans A1 Wang, Cuiyan A1 Chudzicka-Czupała, Agata A1 Tee, Michael A1 López Núñez, María Inmaculada A1 Tripp, Connor A1 Fardin, Mohammad A1 Habib, Hina A1 Tran, Bach A1 Adamus, Katarzyna A1 Anlacan, Joseph A1 Aparicio García, Marta Evelia A1 Grabowski, Damian A1 Hussain, Shahzad A1 Hoang, Men A1 Hetnał, Mateusz A1 Le, Xuan A1 Wenfang Ma, A1 Hai Q. Pham, A1 Reyes, Patrick Wincy A1 Shirazi, Mahmoud A1 Tan, Yilin A1 Tee, Cherica A1 Xu, Linkang A1 Xu, Ziqi A1 Vu, Giang A1 Zhou, Danqing A1 Chan, Natalie A1 Kuruchittham, Vipat A1 McIntyre, Roger A1 Ho, Cyrus A1 Ho, Roger A1 Sears, Samuel AB The novel Coronavirus-2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO) in March 2020, impacting the lifestyles, economy, physical and mental health of individuals globally. This study aimed to test the model triggered by physical symptoms resembling COVID-19 infection, in which the need for health information and perceived impact of the pandemic mediated the path sequentially, leading to adverse mental health outcomes. A cross-sectional research design with chain mediation model involving 4612 participants from participating 8 countries selected via a respondent-driven sampling strategy was used. Participants completed online questionnaires on physical symptoms, the need for health information, the Impact of Event Scale-Revised (IES-R) questionnaire and Depression, Anxiety and Stress Scale (DASS-21). The results showed that Poland and the Philippines were the two countries with the highest levels of anxiety, depression and stress; conversely, Vietnam had the lowest mean scores in these areas. Chain mediation model showed the need for health information, and the perceived impact of the pandemic were sequential mediators between physical symptoms resembling COVID-19 infection (predictor) and consequent mental health status (outcome). Excessive and contradictory health information might increase the perceived impact of the pandemic. Rapid COVID-19 testing should be implemented to minimize the psychological burden associated with physical symptoms, whilst public mental health interventions could target adverse mental outcomes associated with the pandemic. PB Nature Research SN 2045-2322 YR 2021 FD 2021 LK https://hdl.handle.net/20.500.14352/95200 UL https://hdl.handle.net/20.500.14352/95200 LA eng NO Wang, C., Chudzicka-Czupała, A., Tee, M. L., Núñez, M. I. L., Tripp, C., Fardin, M. A., ... & Sears, S. F. (2021). A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans. Scientific reports, 11(1), 6481. https://doi.org/10.1038/s41598-021-85943-7 DS Docta Complutense RD 10 abr 2025