RT Journal Article
T1 Analysis of the Influence of Diabetic Nephropathy in Patients with Diabetic Foot Osteomyelitis
A1 García Álvarez, Yolanda
A1 Álvaro Afonso, Francisco Javier
A1 García-Madrid Martín De Almagro, Marta
A1 Tardaguila García, Aroa
A1 López Moral, Mateo
A1 Lázaro Martínez, José Luis
AB This study analyzed the influence of diabetic nephropathy on the healing prognosis after conservative surgery in diabetic foot osteomyelitis (DFO). A retrospective observational study was carried out between January 2021 and December 2022 and involved 278 outpatients with a diagnosis of DFO at a specialized diabetic foot unit, including 74 (26.62%) patients with DN (group 2) and 204 (73.38%) patients without DN (group 1). There were 266 (95.70%) ulcers on the forefoot, 8 (2.90%) on the midfoot, and 4 (1.45%) on the hindfoot (p = 0.992). The healing rates were 85.1% (n = 63) for group 2 and 81.3% (n = 165) for group 1 (p = 0.457). When exploring the influence of DN on the risk of delayed ulcer healing, the results did not show a significant effect [12 (6; 28) weeks among patients with DN vs. 12 (6; 21) weeks among patients without DN; p = 0.576]. No significant differences were observed in complications, with one (2.59%) death occurring in group 1 (p = 0.296) and three minor amputations being performed in both groups [two (5.13%) amputations in group 1 vs. one amputation (9.09%) in group 2; p = 0.217]. Bone cultures were performed for a total of 190 patients (133 in group 1 and 57 in group 2). Of these, 176 positive bone cultures were isolated: 71 positive bone cultures (57.7%) were monomicrobial cultures in group 1, with 30 (56.6%) in group 2. There were 52 (42.3%) that had at least two microorganisms in group 1, and 23 (43.4%) in group 2 (p = 0.890). The most frequently prescribed oral antibiotic was amoxicillin/clavulanate (43.89%), followed by levofloxacin (28.4%), and trimethoprim/sulfamethoxazole (14.7%). This study shows that DN does not have a significant influence on the healing prognosis of patients with DFO after conservative surgery.
PB MDPI
SN 2077-0383
YR 2023
FD 2023-08-26
LK https://hdl.handle.net/20.500.14352/118922
UL https://hdl.handle.net/20.500.14352/118922
LA eng
NO García-Álvarez, Y.; Álvaro-Afonso, F.J.; García-Madrid, M.; Tardáguila-García, A.; López-Moral, M.; Lázaro-Martínez, J.L. Analysis of the Influence of Diabetic Nephropathy in Patients with Diabetic Foot Osteomyelitis. J. Clin. Med. 2023, 12, 5557. https://doi.org/10.3390/jcm12175557
NO Special Issue Updates on Diabetic Foot Osteomyelitis)
DS Docta Complutense
RD 9 abr 2025