RT Journal Article
T1 Prognostic Factors for Postoperative Chronic Pain after Knee or Hip Replacement in Patients with Knee or Hip Osteoarthritis: An Umbrella Review
A1 Fernández de las Peñas, César
A1 Florencio, Lidiane L.
A1 Llave Rincón, Ana I. de la
A1 Ortega Santiago, Ricardo
A1 Cigarán Méndez, Margarita
A1 Fuensalida Novo, Stella
A1 Plaza Manzano, Gustavo
A1 Arendt Nielsen, Lars
A1 Valera Calero, Juan Antonio
A1 Navarro Santana, Marcos José
AB Knee and hip osteoarthritis are highly prevalent in the older population. Management of osteoarthritis-related pain includes conservative or surgical treatment. Although knee or hip joint replacement is associated with positive outcomes, up to 30% of patients report postoperative pain in the first two years. This study aimed to synthesize current evidence on prognostic factors for predicting postoperative pain after knee or hip replacement. An umbrella review of systematic reviews was conducted to summarize the magnitude and quality of the evidence for prognostic preoperative factors predictive of postoperative chronic pain (>6 months after surgery) in patients who had received knee or hip replacement. Searches were conducted in MEDLINE, CINAHL, PubMed, PEDro, SCOPUS, Cochrane Library, and Web of Science databases from inception up to 5 August 2022 for reviews published in the English language. A narrative synthesis, a risk of bias assessment, and an evaluation of the evidence confidence were performed. Eighteen reviews (nine on knee surgery, four on hip replacement, and seven on both hip/knee replacement) were included. From 44 potential preoperative prognostic factors, just 20 were judged as having high or moderate confidence for robust findings. Race, opioid use, preoperative function, neuropathic pain symptoms, pain catastrophizing, anxiety, other pain sites, fear of movement, social support, preoperative pain, mental health, coping strategies, central sensitization-associated symptoms, and depression had high/moderate confidence for an association with postoperative chronic pain. Some comorbidities such as heart disease, stroke, lung disease, nervous system disorders, and poor circulation had high/moderate confidence for no association with postoperative chronic pain. This review has identified multiple preoperative factors (i.e., sociodemographic, clinical, psychological, cognitive) associated with postoperative chronic pain after knee or hip replacement. These factors may be used for identifying individuals at a risk of developing postoperative chronic pain. Further research can investigate the impact of using such prognostic data on treatment decisions and patient outcomes.
PB MDPI
SN 2077-0383
YR 2023
FD 2023-10-19
LK https://hdl.handle.net/20.500.14352/104845
UL https://hdl.handle.net/20.500.14352/104845
LA eng
NO Fernández-de-Las-Peñas, C., Florencio, L. L., de-la-Llave-Rincón, A. I., Ortega-Santiago, R., Cigarán-Méndez, M., Fuensalida-Novo, S., ... & Navarro-Santana, M. J. (2023). Prognostic Factors for Postoperative Chronic Pain after Knee or Hip Replacement in Patients with Knee or Hip Osteoarthritis: An Umbrella Review. Journal of Clinical Medicine, 12(20), 6624.
NO 2023 Descuento MDPI
DS Docta Complutense
RD 15 dic 2025