TY  - JOUR
AU  - Camano, Sonia
AU  - Lázaro Fernández, Alberto
AU  - Moreno Gordaliza, María Estefanía
AU  - Torres, A. M.
AU  - Lucas, Carmen de
AU  - Humanes, Blanca
AU  - Lázaro, José A.
AU  - Gómez Gómez, María Milagros
AU  - Bosca Gomar, Lisardo
AU  - Tejedor Jorge, Alberto
PY  - 2010
DO  - 10.1124/jpet.110.165779.
SN  - 0022-3565
UR  - https://hdl.handle.net/20.500.14352/42738
T2  - Journal of Pharmacology and Experimental Therapeutics
AB  - A major area in cancer therapy is the search for protective strategies against cisplatin-induced nephrotoxicity. We investigated the protective effect of cilastatin on cisplatininduced injury to renal proximal tubular cells. Cilastatin is a specific...
LA  - spa
M2  - 419
PB  - American Society for Pharmacology and Experimental Therapeutics
KW  - RPTECs
KW  - Renal proximal tubular epithelial cells
KW  - OCT
KW  - Organic cation transporter
KW  - DHP-I
KW  - Dehydrodipeptidase I
KW  - DAPI
KW  - 6-diamidino-2-phenylindole
KW  - PBS
KW  - Phosphate-buffered saline
KW  - PI
KW  - Propidium iodide
KW  - FITC
KW  - Fluorescein isothiocyanate
KW  - LDH
KW  - Lactate dehydrogenase
KW  - MTT
KW  - 5-dimethylthiazol-2-yl)-2
KW  - 5-diphenyltetrazolium
KW  - Mitochondrial transmembrane potential
KW  - CCCP
KW  - Carbonyl cyanide 3-chlorophenylhydrazone
KW  - ICP/MS
KW  - Inductively coupled plasma/mass spectrometry
KW  - SEC
KW  - Size exclusion
KW  - TNF
KW  - Tumor necrosis factor
KW  - Fas-L
KW  - Fas ligand
KW  - PCR
KW  - Polymerase chain reaction
KW  - RPLPO
KW  - Ribosomal phosphoprotein large PO subunit
KW  - ANOVA
KW  - Analysis of variance
KW  - CFUs
KW  - Colony-forming units
KW  - Pt
KW  - Platinum
KW  - Ir
KW  - Iridium
TI  - Cilastatin Attenuates Cisplatin-Induced Proximal Tubular Cell Damage
TY  - journal article
VL  - 334
ER  -