TY - JOUR AU - Sevilla-Montero, J AU - Munar-Rubert, O. AU - Pino-Fadón, J. AU - Aguilar-Latorre, C. AU - Villegas-Esguevillas, M. AU - Agrò, M. AU - Choya-Foces, C. AU - Martínez-Ruiz, A. AU - Balsa, E. AU - Muñoz-Calleja, C. AU - Gómez-Punter, R.M. AU - Vázquez-Espinosa, E. AU - Cogolludo Torralba, Ángel Luis AU - Calzada, M.J. AU - Climent Flórez, Belén PY - 2022 DO - 10.1016/j.freeradbiomed.2022.09.026 UR - https://hdl.handle.net/20.500.14352/130860 T2 - Free Radical Biology and Medicine AB - Chronic obstructive pulmonary disease (COPD), whose main risk factor is cigarette smoking (CS), is one of the most common diseases globally. Some COPD patients also develop pulmonary hypertension (PH), a severe complication that leads to premature... LA - eng M2 - 9 PB - Elsevier KW - COPD KW - Cigarette smoke KW - Mitochondrial superoxide KW - NADPH oxidases KW - NRF2 KW - sGC KW - Vasodilation KW - Pulmonary artery TI - Cigarette smoke induces pulmonary arterial dysfunction through an imbalance in the redox status of the soluble guanylyl cyclase TY - journal article VL - 193 ER -