RT Journal Article
T1 EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
A1 Reche Gallardo, Pedro Antonio
A1 Zhang, Hong
A1 Glutting, John-Paul
A1 Reinherz, Ellis L
AB EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/
PB Oxford University Press
SN 1367-4803
YR 2005
FD 2005
LK https://hdl.handle.net/20.500.14352/50385
UL https://hdl.handle.net/20.500.14352/50385
LA eng
DS Docta Complutense
RD 20 abr 2025