RT Journal Article T1 The Brainstem-Vermis and Brainstem-Tentorium Angles in the Fetus: A Study of Their Reproducibility by Fetal Magnetic Resonance Imaging and Their Evolution Along the Gestation A1 Joigneau Prieto, Laura A1 Ruíz, Yolanda A1 Pérez, Laura A1 Bravo Arribas, Coral A1 Aguado, Alejandra A1 Álvarez Mon, Melchor A1 Ortega, Miguel Ángel A1 Marín Rodríguez, Carlos A1 León Luis, Juan Antonio AB AimTo assess the reproducibility of brainstem-vermis (BV) and brainstem-tentorium (BT) angles measured by fetal Magnetic Resonance Imaging (MRI) during second half of pregnancy in normal and abnormal fetuses. Secondly, to assess reproducibility of two alternative methodologies to measure the brainstem-tentorium angle (BT1 and BT2) proposed by our group that could be more reliable in fetuses with posterior fossa fluid collection (PFFC) anomalies. Finally, to describe the evolution of BV and BT angles along gestation in normal fetuses.MethodsWe conducted a cross-sectional study of BV and BT angles obtained by MRI performed at our center, in 22 fetuses with PFFC and 8 fetuses without PFFC to calculate both angles’ reproducibility and the correlation between them and the gestational age.ResultsWe found good interobserver reproducibility for the BV, BT1 and BT2 angles (Intraclass correlation coefficient: 0.98; 0.89 and 0.88 for each of these angles, with p < 0.001). In patients with PFFC the BT angle could not always be measured. BT angle presented a positive relationship with gestational age (p = 0.002) but BV angle stayed stable. The measurements of BV, BT1, and BT2 angles can be reliably performed by MRI with good interobserver reproducibility.ConclusionBV angle stays stable during pregnancy, whereas BT angle tends to augment with gestational age. PB Frontiers Media SN 2296-858X YR 2022 FD 2022-05-26 LK https://hdl.handle.net/20.500.14352/115130 UL https://hdl.handle.net/20.500.14352/115130 LA eng NO Prieto LJ, Ruiz Y, Pérez L, Bravo C, Aguado A, Alvarez-Mon M, Ortega MA, Marín C, De León-Luis J. The Brainstem-Vermis and Brainstem-Tentorium Angles in the Fetus: A Study of Their Reproducibility by Fetal Magnetic Resonance Imaging and Their Evolution Along the Gestation. Front Med (Lausanne). 2022 May 26;9:878906 NO Instituto de Salud Carlos III NO Unión Europea NO Comunidad Autónoma de Madrid NO Halekulani, S.L DS Docta Complutense RD 24 abr 2025