TY - JOUR AU - Fagagnini, Andrea AU - Pica, Andrea AU - Fasoli, Sabrina AU - Montioli, Riccardo AU - Donadelli, Massimo AU - Cordani, Marco AU - Butturini, Elena AU - Acquasaliente, Laura AU - Picone, Delia AU - Gotte, Giovanni PY - 2017 DO - 10.1042/BCJ20170541 SN - 0264-6021 UR - https://hdl.handle.net/20.500.14352/98862 T2 - Biochemical Journal AB - Onconase® (ONC), a protein extracted from the oocytes of the Rana pipiens frog, is a monomeric member of the secretory 'pancreatic-type' RNase superfamily. Interestingly, ONC is the only monomeric ribonuclease endowed with a high cytotoxic activity.... LA - eng M2 - 3767 PB - Portland Press TI - Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells TY - journal article VL - 474 ER -