TY  - JOUR
AU  - Canales Mayordomo, María Ángeles
AU  - Bargsten, Katja
AU  - Bennani, Youssef L.
AU  - Díaz, Fernando J.
AU  - Jiménez Barbero, Jesús
AU  - Oliva, María A.
AU  - Prota, Andrea E.
AU  - Rodríguez Salarichs, J.
AU  - Steinmetz, Michel O.
PY  - 2020
DO  - 10.1021/acs.jmedchem.0c00855
UR  - https://hdl.handle.net/20.500.14352/129977
T2  - Journal of Medicinal Chemistry
AB  - Noscapine is a natural alkaloid that is used as an antitussive medicine. However, it also acts as a weak anticancer agent in certain in vivo models through a mechanism that is largely unknown. Here, we performed structural studies and show that the...
LA  - eng
M2  - 8495
PB  - ACS publications
KW  - Matrix CORCEMA analysis
KW  - Complete relaxation
KW  - Colchicine
KW  - Mechanism
TI  - Structural basis of noscapine activation for tubulin binding
TY  - journal article
VL  - 63
ER  -