TY  - JOUR
AU  - De Pablo Moreno, Juan Andrés
AU  - González-Brusi, Leopoldo
AU  - Miguel Batuecas, Andrea
AU  - Bermejo Álvarez, Pablo
AU  - Revuelta Rueda, Luis
AU  - Liras Martín, Antonio
PY  - 2025
DO  - 10.1371/journal.pone.0321864
SN  - 1932-6203
UR  - https://hdl.handle.net/20.500.14352/123078
T2  - PLOS One
AB  - Factor V deficiency is a congenital coagulation disorder characterized by the absence or malfunction of factor V (FV). The purpose of this study was to develop a viable FV-deficient mouse model using CRISPR/Cas9 technology. A viable pathological model...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Factor V deficiency
KW  - Murine model
KW  - CRISPR/Cas9
KW  - Knock-in
KW  - Ultra-rare disease
KW  - Coagulation
TI  - Development of a novel and viable knock-in factor V deficiency murine model: Utility for an ultra-rare disease
TY  - journal article
VL  - 20
ER  -