RT Journal Article
T1 Modeling the Succinic Acid Bioprocess: A Review
A1 Escanciano, Itziar A.
A1 Wojtusik, Mateusz
A1 Esteban, Jesus
A1 Ladero Galán, Miguel
A1 Santos Mazorra, Victoria Eugenia
AB Succinic acid has attracted much interest as a key platform chemical that can be obtained in high titers from biomass through sustainable fermentation processes, thus boosting the bioeconomy as a critical production strategy for the future. After several years of development of the production of succinic acid, many studies on lab or pilot scale production have been reported. The relevant experimental data reveal underlying physical and chemical dynamic phenomena. To take advantage of this vast, but disperse, kinetic information, a number of mathematical kinetic models of the unstructured non-segregated type have been proposed in the first place. These relatively simple models feature critical aspects of interest for the design, control, optimization and operation of this key bioprocess. This review includes a detailed description of the phenomena involved in the bioprocesses and how they reflect on the most important and recent models based on macroscopic and metabolic chemical kinetics, and in some cases even coupling mass transport.
PB MDPI
SN 2311-5637
YR 2022
FD 2022
LK https://hdl.handle.net/20.500.14352/72219
UL https://hdl.handle.net/20.500.14352/72219
LA eng
DS Docta Complutense
RD 28 abr 2025