RT Journal Article T1 Novel Insights into the Transmission of SARS-CoV-2 Through the Ocular Surface and its Detection in Tears and Conjunctival Secretions: A Review A1 Güemes Villahoz, Noemi A1 Burgos Blasco, Bárbara A1 Vidal Villegas, Beatriz A1 García Feijoo, Julián A1 Arriola Villalobos, Pedro A1 Martínez De La Casa Fernández-Borrella, José María A1 Díaz Valle, David A1 Konstas, Anastasios Georgios AB SARS-CoV-2 is a highly transmissible virus that spreads mainly via person-to-person contact through respiratory droplets, or through contact with contaminated objects or surfaces from an infected person. At present we are passing through a phase of slow and painful understanding of the origin, epidemiological profile, clinical spectrum, and risk profile of the virus. To the best of our knowledge there is only limited and contradictory evidence concerning SARS-CoV-2 transmission through other routes. Importantly, the eye may constitute not only a potential site of virus replication but also an alternative transmission route of the virus from the ocular surface to the respiratory and gastrointestinal tract. It is therefore imperative to gain a better insight into the potential ophthalmological transmission route of the virus and establish directions on best practice and future models of care for ophthalmological patients. This review article critically evaluates available evidence on the ophthalmological mode of viral transmission and the value of earlier identification of the virus on the eye. More evidence is urgently needed to better evaluate the need for protective measures and reliable ocular diagnostic tests to diminish further pandemic spread. PB Springer Healthcare SN 0741-238X YR 2020 FD 2020-08-18 LK https://hdl.handle.net/20.500.14352/6491 UL https://hdl.handle.net/20.500.14352/6491 LA eng NO Güemes-Villahoz, N., Burgos Blasco, B., Vidal Villegas, B. et al. Novel Insights into the Transmission of SARS-CoV-2 Through the Ocular Surface and its Detection in Tears and Conjunctival Secretions: A Review. 2020. DOI.org (Datacite), https://doi.org/10.6084/M9.FIGSHARE.12601931. NO En O.A. en la web del editor.Recibido: 26de mayo de 2020 DS Docta Complutense RD 6 abr 2025