RT Journal Article
T1 Psychomotor Development of Children from an Iodine-Deficient Region
A1 Costeira, Maria José
A1 Oliveira, Pedro
A1 Correia Santos, Nadine
A1 Ares, Susana
A1 Sáenz-Rico de Santiago, María Belén
A1 Morreale de Escobar, Gabriella
A1 Almeida Palha, Joana
AB Objectives To assess the psychomotor development of the progeny of women from a moderately iodine deficient area for whom thyroid function during pregnancy was measured. Study design The development of 86 children was assessed by the Bayley Scale of Infant Development at 12, 18,and 24 months. Results Maternal serum free thyroxine (FT4) levels in the first trimester of pregnancy were the major determinant ofpsychomotor development at 18 and 24 months. Children born from mothers with FT4 levels <25th percentile (<10pg/mL) had an OR of 2.1 for mild-to-severe delay. Furthermore, alterations in behavior were already observed at 12 months and were related to subsequent changes in development. Neonatal thyroid status did not influence development. Conclusions This study highlights the need to implement active measures of iodine supplementation pericon ceptionally and during pregnancy and lactation because the negative effects on development and behavior mightbe prevented through preemptive action
PB Elservier
SN 0022-3476
SN 1097-6833
YR 2011
FD 2011-02-25
LK https://hdl.handle.net/20.500.14352/100132
UL https://hdl.handle.net/20.500.14352/100132
LA eng
NO Costeira, M.J., Oliveira, P., Santos, N.C., Ares, S., Saenz-Rico, B., De Escobar, G.M.and Palha, J.A. (2011). The Journal of Pediatrics, 159(3), 447-453. https://doi.org/10.1016/j.jpeds.2011.02.034
NO Estudio realizado por un equipo de investigación interdisciplinar dada la naturaleza de la población y el objeto de estudio.Supported by the Portuguese Science Foundation (FCT)- FEDER (POCTI_PSI_60948_2004) and Integrated Actions for exchange of scientists ‘‘Portugal-Spain E-84/ 2006’’ (by Fundacao para a Ciencia e Tecnologia, Portugal and by Ministerio de Educacion y Ciencia, Spain).
NO Supported by the Portuguese Science Foundation (FCT)- FEDER (POCTI_PSI_60948_2004) and Integrated Actions for exchange of scientists ‘‘Portugal-Spain E-84/ 2006’’ (by Fundacao para a Ciencia e Tecnologia, Portugal and by Ministerio de Educacion y Ciencia, Spain).
NO POCTI_PSI_60948_2004
DS Docta Complutense
RD 8 abr 2025