RT Journal Article
T1 Increased individual homozygosity is correlated with low fitness in a fragmented lizard population
A1 Pérez Tris, Javier
A1 Llanos Garrido, Alejandro
A1 Bloor, Paul
A1 Carbonell Alanís, Roberto
A1 Tellería Jorge, José Luis
A1 Santos Martínez, Tomás
A1 Díaz González-Serrano, José Augusto
AB Isolation owing to anthropogenic habitat fragmentation is expected to increase the homozygosity of individuals, which might reduce their fitness as a result of inbreeding depression. Using samples from a fragmented population of the lizard Psammodromus algirus, for which we had data about two correlates of fitness, we genotyped individuals for six microsatellite loci that correctly capture genome-wide individual homozygosity of these lizards (as validated with an independent sample of lizards genotyped for both these microsatellites and > 70 000 single nucleotide polymorphisms). Our data revealed genetic structure at a very small geographical scale, which was compatible with restricted gene flow among populations disconnected in a matrix of inhospitable habitat. Lizards from the same fragment were genetically more related to one another than expected by chance, and individual homozygosity was greater in small than in large fragments. Within fragments, individual homozygosity was negatively associated with adult body size and clutch mass, revealing a link among reduced gene flow, increased homozygosity and lowered fitness that might reduce population viability deterministically. Our results contribute to mounting evidence of the impact of the loss of genetic diversity on fragmented wild populations.
PB Oxfrod University Press
SN 0024-4066
YR 2019
FD 2019-09-05
LK https://hdl.handle.net/20.500.14352/12835
UL https://hdl.handle.net/20.500.14352/12835
LA eng
NO Pérez Tris, J., Llanos Garrido, A., Bloor, P. et al. «Increased Individual Homozygosity Is Correlated with Low Fitness in a Fragmented Lizard Population». Biological Journal of the Linnean Society, vol. 128, n.o 4, diciembre de 2019, pp. 952-62. DOI.org (Crossref), https://doi.org/10.1093/biolinnean/blz144.
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Universidad Complutense de Madrid/Comunidad de Madrid
DS Docta Complutense
RD 8 abr 2025