TY - JOUR AU - Moyano-Cires Ivanoff, Paula Viviana AU - Flores, Andrea AU - García, Jimena AU - García Sánchez, José Manuel AU - Anadón Baselga, María José AU - Frejo Moya, María Teresa AU - Sola Vendrell, Emma AU - Pelayo Alarcón, Adela AU - Pino Sans, Javier Del PY - 2021 DO - 10.1016/j.fct.2021.112614 SN - 0278-6915 UR - https://hdl.handle.net/20.500.14352/113306 T2 - Food and Chemical Toxicology AB - Bisphenol-A (BPA), a widely used plasticizer, induces cognitive dysfunctions following single and repeated exposure. Several studies, developed in hippocampus and cortex, tried to find the mechanisms that trigger and mediate these dysfunctions, but... LA - eng M2 - 1 PB - Elsevier KW - AChE KW - Bisphenol A KW - ChAT KW - HDAC2 KW - NGF KW - P75(NTR) KW - SN56 basal forebrain cholinergic neurons KW - TrkA TI - Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75NTR signaling disruption. TY - journal article VL - 157 ER -