RT Journal Article
T1 Influence of the severity of osteogenesis imperfecta on cranial measurements
A1 Nova García, Manuel Joaquín De
A1 García de Sola, Rafael
A1 Burgueño Torres, Laura
AB Osteogenesis Imperfecta (OI) is a disease that causes bone fragility and deformities, affecting both the cranial base and the craniocervical junction, and may lead to other neurological disorders. A retrospective cross-sectional study was carried out based on cephalometric analysis of the cranial base in a sample of patients with OI, in lateral skull radiographs and magnetic resonance imaging (MRI), comparing them with a sample of age-matched controls. When the different variables of the craniocervical junction were analyzed, significance was found in comparisons with the different age groups. All measurements of the variables studied stabilized as growth progressed. For most of the variables, the severity of the disease influences the measurements of the skull base, with statistically significant differences. Both age and severity of the disease are factors that directly influence the anatomy of the craniocervical junction in these patients and may serve as indicators in the early detection and prevention of other derived alterations.
PB MDPI
SN 2227-9067
YR 2023
FD 2023-06-08
LK https://hdl.handle.net/20.500.14352/102325
UL https://hdl.handle.net/20.500.14352/102325
LA eng
NO De Nova-García MJ, Sola RG, Burgueño-Torres L. Influence of the Severity of Osteogenesis Imperfecta on Cranial Measurements. Children (Basel). 2023 Jun 8;10(6):1029
DS Docta Complutense
RD 8 abr 2025