RT Journal Article T1 Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar. A1 Martínez Rodríguez, Natalia A1 Barona Dorado, Cristina A1 Martín-Arés, María A1 Cortés Bretón Brinkmann, Jorge A1 Martínez González, José María AB Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration.Study design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to articaine hydrochloride with epinephrine 1:100,000 and lidocaine hydrochloride with epinephrine 1:100,000. The variables analysed were latency period, duration of anaesthetic effect, tolerance and adverse reactions.Results: Both the latency period and the duration of anaesthetic effect were greater for articaine, although the differences were not statistically significant. Latency: mean difference of 2.70 ± 2.12 minutes (95%CI of -1.51 minutes - 6.92 minutes).Duration: mean difference of -33 minutes 5 seconds ± 31 minutes (95% CI -1 hour 35 minutes - 29 minutes). There were 4 adverse events that did not require the patients to be withdrawn from the study.Conclusions: The anaesthetics in this study have very similar properties for use in surgery and have demonstrated a good safety and tolerability profile. PB Medicina Oral SN 1698-4447 YR 2012 FD 2012-03 LK https://hdl.handle.net/20.500.14352/129125 UL https://hdl.handle.net/20.500.14352/129125 LA eng NO Martínez-Rodríguez N, Barona-Dorado C, Martín-Arés M, Cortés-Bretón-Brinkman J, Martínez-González JM. Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar. Med Oral Patol Oral Cir Bucal. 2012 Mar 1;17(2):e345-51. doi: 10.4317/medoral.17414. DS Docta Complutense RD 19 mar 2026