RT Journal Article
T1 Repeatability of macular and optic nerve head measurements by optical coherence tomography angiography in healthy children
A1 Pérez García, Pilar
A1 Morales Fernández, Laura
A1 Fernández Vigo, José Ignacio
A1 Sáenz Francés, Federico
A1 Burgos Blasco, Bárbara
A1 Güemes Villahoz, Noemi
A1 Oribio Quinto, Carlos
A1 García Feijoo, Julián
A1 Martínez De La Casa Fernández-Borrella, José María
AB Aims: To evaluate the repeatability of the peripapillary and macular vascular parameters using optical coherence tomography angiography (OCT-A) in healthy children.Materials and methods: Cross-sectional study including 34 eyes of 34 healthy children. After a complete medical examination, two consecutive OCT-A exams were done using AngioPlex Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA, USA) in the same session. The scan area used was 6 × 6 mm for the analysis of the superficial vascular plexus (SVP) in the macula, and 4.5 × 4.5 mm for the peripapillary plexus. To study the repeatability of the measurements, the intraclass correlation coefficient (ICC) and the coefficient of variation (CV) of each pair of exams were calculated.Results: The mean age of the children included was 10.77 ± 2.49 years (range 6 to 15 years). Good and excellent ICCs were obtained for all the parameters considered. Peripapillary vascular parameters showed greater reproducibility than macular ones (global peripapillary perfusion density (pPD): ICC = 0.834 CV = 0.89% vs. whole macular area PD (w-mPD): ICC = 0.697 CV = 3.49%; global peripapillary flux index (FI): ICC = 0.858 CV = 1.28%; whole macular area vascular density (VD): ICC = 0.699 CV = 3.30%). Amongst the macular parameters, the characteristics of the foveal avascular zone (FAZ) were the ones showing higher rates of repeatability (FAZ circularity: ICC = 0.858 CV = 8.83%).Conclusion: OCT-A is a non-invasive, time-efficient technology that may be useful in the evaluation of the retinal and peripapillary vascular network in healthy children. The repeatability of the measures will allow the follow-up and evaluation of any change occurring in the macular or optic nerve perfusion.
PB Taylor & Francis
SN 0271-3683
YR 2021
FD 2021-04-13
LK https://hdl.handle.net/20.500.14352/8034
UL https://hdl.handle.net/20.500.14352/8034
LA eng
NO Pérez García, P., Morales Fernández, L., Fernández Vigo, J. I. et al. «Repeatability of Macular and Optic Nerve Head Measurements by Optical Coherence Tomography Angiography in Healthy Children». Current Eye Research, vol. 46, n.o 10, octubre de 2021, pp. 1574-80. DOI.org (Crossref), https://doi.org/10.1080/02713683.2021.1908568.
DS Docta Complutense
RD 10 abr 2025