RT Journal Article
T1 Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
A1 Miguel Díez, Javier De
A1 Jiménez García, Rodrigo
A1 Hernández Barrera, V.
A1 Puente Maestu, Luis
A1 Girón Matute, Walther Iván
A1 Miguel Yanes, José María De
A1 Méndez Bailón, Manuel
A1 Villanueva Orbaiz, M. Rosa Rita
A1 Albaladejo Vicente, Romana
A1 López De Andrés, Ana Isabel
AB Background: We examine trends (2001–2015) in the use of non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV) among patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AE-COPD).Methods: Observational retrospective epidemiological study, using the Spanish National Hospital Discharge Database.Results: We included 1,431,935 hospitalizations (aged ≥40 years) with an AE-COPD. NIV use increased significantly, from 1.82% in 2001–2003 to 8.52% in 2013–2015, while IMV utilization decreased significantly, from 1.39% in 2001–2003 to 0.67% in 2013–2015. The use of NIV + invasive mechanical ventilation (IMV) rose significantly over time (from 0.17% to 0.42%). Despite the worsening of clinical profile of patients, length of stay decreased significantly over time in all types of ventilation. Patients who received only IMV had the highest in-hospital mortality (IHM) (32.63%). IHM decreased significantly in patients with NIV + IMV, but it remained stable in those receiving isolated NIV and isolated IMV. Factors associated with use of any type of ventilatory support included female sex, lower age, and higher comorbidity.  Conclusions: We found an increase in NIV use and a decline in IMV utilization to treat AE-COPD among hospitalized patients. The IHM decreased significantly over time in patients who received NIV + IMV, but it remained stable in patients who received NIV or IMV in isolation.
PB MDPI
SN 2077-0383
YR 2019
FD 2019-10-04
LK https://hdl.handle.net/20.500.14352/12577
UL https://hdl.handle.net/20.500.14352/12577
LA eng
NO Miguel Díez, J., Jiménez García, R., Hernández Barrera, V. et al. «Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015». Journal of Clinical Medicine, vol. 8, n.o 10, octubre de 2019, p. 1621. Crossref, https://doi.org/10.3390/jcm8101621.
NO Instituto de Salud Carlos III/Fondo Europeo de Desarrollo Regional
NO Sociedad Española de Neumología y Cirugía Torácica
DS Docta Complutense
RD 17 abr 2025