RT Journal Article T1 Comparative Clinical Study of Two Tooth Whitening Protocols A1 Oteo Morilla, Carlos A1 Oteo Calatayud, Carlos A1 Oteo Calatayud, María Dolores A1 Oteo Calatayud, Jesús A1 Cantero-Gómez, María A1 Kewalramani NK, AB This study aimed to clinically evaluate the effectiveness of two different at-home whitening protocols and to determine which is more effective: applying the whitening gel (16% carbamide peroxide) every 24 hours (Group A) or every 48 hours (Group B) for 2 weeks. Group C received a placebo gel (glycerin) without peroxide, which was applied every 24 hours for 2 weeks. The differences in terms of tooth sensitivity were also analyzed. A sample of 60 patients was divided into three groups of 20 patients. To compare the groups, color measurements were made using a spectrophotometer, and Student t test was used for independent samples. The confidence level was set at 95% (P ≤ .05). No statistically significant differences were found between Groups A and B (P > .05). The study concluded that 16% carbamide peroxide was equally effective when applied with either protocol and obtained the same results, but the 48-hour application protocol produced less sensitivity than the 24-hour application protocol. PB Quintessence SN 0198-7569 YR 2023 FD 2023-09-21 LK https://hdl.handle.net/20.500.14352/119697 UL https://hdl.handle.net/20.500.14352/119697 LA eng NO Oteo-Morilla C, Cantero-Gómez M, Oteo-Calatayud C, Oteo-Calatayud J, Oteo Calatayud MD, Kewalramani NK. Comparative Clinical Study of Two Tooth Whitening Protocols. Int J Periodontics Restorative Dent. 2023 Sep-Oct;43(5):630-637. doi: 10.11607/prd.6406 DS Docta Complutense RD 25 dic 2025