RT Journal Article T1 Short and medium term effects of low level laser therapy on periodontal status in lingual orthodontic patients A1 Abellán, Rosa A1 Gómez, Clara A1 Oteo Calatayud, María Dolores A1 Scuzzo, Giuseppe A1 Palma Fernández, Juan Carlos AB Objective: The purpose of this study was to evaluate the short- and medium-term effects of low-level laser therapy (LLLT) applied in repeated doses in adults with a healthy periodontium treated by lingual orthodontic appliances.Background data: Plaque accumulation, in combination with difficulty in removing it in lingual orthodontic patients, can cause gingival inflammation.Methods: Twelve orthodontic patients scheduled for fixed lingual orthodontic treatment were selected. Clinical measurements [visible plaque index (VPI), bleeding on probing (BOP), and probing depth (PD), and collection of gingival crevicular fluid (GCF)], which was used to measure the levels of interleukin-1beta (IL-1β) and tumor necrosis factor alpha (TNF-α), was performed before bonding the lingual device, and at the short-term (1, 2, 3 months) and medium-term (12 months) follow-up appointments. For each patient, quadrant 1 or 2 was randomly chosen for irradiation by a diode laser (λ = 670 nm, 190 mW, 6.05 W/cm(2), 60 sec/ tooth) (Laser Group) and the contralateral quadrant was used as the Control Group.Results: In both studied groups, a slight worsening of the periodontal condition was observed, which was evident at the 3rd month follow-up and which was mainly at the lingual side in the Control Group. The levels of IL-1β in the GCF were significantly increased in the Control Group compared with the Laser Group at the 2nd and 3rd months after bonding. At the 12th month follow-up, an improvement of the inflammation was observed in both groups in the study.Conclusions: LLLT showed short-term effects by preventing a substantial increase in IL-1β levels. At medium-term follow-up, LLLT diminished VPI, BOP, and PD scores. PB SAGE SN 2578-5478 YR 2016 FD 2016-04-15 LK https://hdl.handle.net/20.500.14352/129079 UL https://hdl.handle.net/20.500.14352/129079 LA eng NO Abellán R, Gómez C, Oteo MD, Scuzzo G, Palma JC. Short- and Medium-Term Effects of Low-Level Laser Therapy on Periodontal Status in Lingual Orthodontic Patients. Photomed Laser Surg. 2016 Jul;34(7):284-90. doi: 10.1089/pho.2015.4024 NO Fundación Eugenio Rodriguez Pascual (España) NO Ministerio de Ciencia, Innovación y Universidades (España) NO Di&B Spanish Enterprise - lending the Periowave System DS Docta Complutense RD 23 mar 2026