TY - JOUR AU - Ramirez-Carracedo, Rafael AU - Tesoro, Laura AU - Hernández, Ignacio AU - Diez-Mata, Javier AU - Piñeiro, David AU - Hernández Jiménez, Macarena AU - Zaragoza, Carlos AU - Zamorano Gómez, José Luis PY - 2020 DO - 10.3390/biom10081167 UR - https://hdl.handle.net/20.500.14352/113569 T2 - Biomolecules AB - Toll-like receptor 4 (TLR4) contributes to the pathogenesis of coronary ischemia/reperfusion (IR). To test whether the new TLR4 antagonist, ApTOLL, may prevent coronary IR damage, we administered 0.078 mg/kg ApTOLL or Placebo in pigs subjected to IR,... LA - eng PB - MDPI KW - ApTOLL KW - Acute myocardial infarction KW - Cytokines KW - Matrix metalloproteinases KW - Toll-like receptor 4 TI - Targeting TLR4 with ApTOLL Improves Heart Function in Response to Coronary Ischemia Reperfusion in Pigs Undergoing Acute Myocardial Infarction TY - journal article VL - 10 ER -