TY - JOUR AU - Alonso Gómez, Cristina AU - Satta, Valentina AU - Díez Gutiérrez, Paula AU - Fernández Ruiz, Javier AU - Sagredo Ezquioga, Onintza PY - 2022 DO - 10.1016/j.neuropharm.2021.108914 SN - 0028-3908 UR - https://hdl.handle.net/20.500.14352/71321 T2 - Neuropharmacology AB - Dravet Syndrome (DS) is caused by mutations in the Scn1a gene encoding the α1 subunit of the sodium channel Nav1.1, which results in febrile seizures that progress to severe tonic-clonic seizures and associated comorbidities. Treatment with... LA - eng M2 - 108914 PB - Elsevier KW - Behavioural comorbidities KW - Cannabinoids KW - Dravet syndrome KW - Glial reactivity KW - Infantile epileptic refractory syndromes KW - Seizuring activity KW - Syn-Cre/Scn1a(WT/A1783V) mice KW - β-caryophyllene. TI - Preclinical investigation of β-caryophyllene as a therapeutic agent in an experimental murine model of Dravet syndrome TY - journal article VL - 205 ER -