RT Journal Article T1 Management of an outbreak of brucellosis due to B. melitensis in dairy cattle in Spain A1 Álvarez Sánchez, Julio A1 Sáez, Jose Luis A1 García Benzaquén, Nerea A1 Serrat, Carles A1 Pérez Sancho, Marta A1 González Domínguez, Sergio A1 Ortega, Maria Jesús A1 Gou, Josep A1 Carbajo, Lucio A1 Garrido, Fulgencio A1 Goyache Goñi, Joaquín A1 Domínguez Rodríguez, Lucas José AB Brucella melitensis is a major human and animal pathogen, with a wide host range that includes all domestic ruminant species, although small ruminants are its preferred hosts. Outbreaks in cattle due to B. melitensis have become a worldwide emerging problem particularly difficult to control due to the lack of knowledge on the epidemiology in this host species and of an effective vaccine. However, combination of molecular tools and strict biosecurity measures can help to solve these difficulties and eventually eradicate the disease from infected herds. In the present report, management of an outbreak in Spain involving four farms, more than 2000 cattle and several human cases is described. Application of Multiple Locus VNTR Analysis (MLVA) allowed identifying the most likely source of infection. Stamping out and test-and-slaughter strategies were applied, proving their usefulness to control the outbreak depending on infection level, and without the need of other alternative measures. PB Elsevier SN 0034-5288 YR 2011 FD 2011-04 LK https://hdl.handle.net/20.500.14352/93436 UL https://hdl.handle.net/20.500.14352/93436 LA eng NO Alvarez, J., Sáez, J. L., García, N., Serrat, C., Pérez-Sancho, M., González, S., Ortega, M. J., Gou, J., Carbajo, L., Garrido, F., Goyache, J., & Domínguez, L. (2011). Management of an outbreak of brucellosis due to B. melitensis in dairy cattle in Spain. Research in veterinary science, 90(2), 208–211. https://doi.org/10.1016/j.rvsc.2010.05.028 NO 2010 Elsevier Ltd. All rights reserved. DS Docta Complutense RD 4 ago 2024