TY - JOUR AU - García Carbonero, Rocío AU - Salazar, Ramon PY - 2022 DO - 10.1136/jitc-2021-003255 SN - 2051-1426 UR - https://hdl.handle.net/20.500.14352/117223 T2 - Journal for immunotherapy of cancer AB - Background VCN-01 is an oncolytic adenovirus (Ad5 based) designed to replicate in cancer cells with dysfunctional RB1 pathway, express hyaluronidase to enhance virus intratumoral spread and facilitate chemotherapy and immune cells extravasation into... LA - eng PB - BMJ Publishing Group KW - Clinical trials as topic KW - Gastrointestinal neoplasms KW - Oncolytic virotherapy KW - Tumor microenvironment TI - Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors TY - journal article VL - 10 ER -