RT Journal Article T1 Validity of a Spanish Version of the Leicester Cough Questionnaire in Children With Cystic Fibrosis T2 Validación de la versión en español del Cuestionario de Tos Leicester en niños con fibrosis quística A1 Del Corral Núñez-Flores, Tamara A1 Percegona, Janaína A1 López, Núria A1 Valiente, Andrea A1 Garriga, María A1 Seborga, Melisa A1 Vilaró, Jordi AB Background: Cystic fibrosis (CF) patients present chronic cough as one of the main symptoms, which has an important effect on quality of life and social relations. Our goal was to validate the Spanish version of the Leicester Cough Questionnaire (LCQ) in a group of children and teenagers with CF.Methods: After adapting to Spanish by standardized translation and retro-translation methodology, a sample of 58 stable CF patients from 7 to 18 years were recruited from three CF specialized centers in Spain. The questionnaire was administered twice; the second administration (LCQ2) was performed between 2-4 weeks later than the first one (LCQ1), in order to analyse the reliability and validity of the Spanish version. To correlate results with health related quality of life (HRQoL) we used the Cystic Fibrosis Questionnaire-Revised (CFQ-R).Results: Population was composed by 62% male, age 11.7 ± 3.1 years and body mass index (BMI) 19 ± 3 kg/m(2). Total scores from LCQ were: LCQ1 19 (17.75-21) vs LCQ2 19 (16-21) (P=.199). Cronbach's Alpha coefficient was 0.83 for the LCQtotal and for each specific domain was: 0.82 LCQphysical; 0.74 LCQpsychological and 0.62 LCQsocial. Intraclass correlation coefficient was: 0.69 LCQphysical; 0.59 LCQpsychological; 0.45 LCQsocial and 0.71 LCQtotal (good reliability). Relations with CFQ-R showed moderated and significant results: for the LCQtotal: respiratory symptom domain r = 0,51 (P<.001) and physical capacity domain r = 0,62 (P<.05).Conclusion: The Spanish version of the Leicester Cough Questionnaire is reliable and valid for children and adolescents with CF and it has good relations with health related quality of life in this population. PB Elsevier España, S.L.U. SN 0300-2896 YR 2016 FD 2016-02-01 LK https://hdl.handle.net/20.500.14352/94346 UL https://hdl.handle.net/20.500.14352/94346 LA eng NO Del Corral T, Percegona J, López N, Valiente A, Garriga M, Seborga M, Vilaró J. Validity of a Spanish Version of the Leicester Cough Questionnaire in Children With Cystic Fibrosis. Arch Bronconeumol. 2016 Feb;52(2):63-9. DS Docta Complutense RD 8 abr 2025