RT Journal Article
T1 A cephalometric method to diagnosis the craniovertebral junction abnormalities in osteogenesis imperfecta patients
A1 Rios Rodenas, Mercedes
A1 Nova García, Manuel Joaquín De
A1 Gutiérrez Díez, Mª Pilar
A1 Feijoo García, Gonzalo
A1 Mourelle Martínez, Rosa
A1 Garcilazo Ambriz, Mario
A1 Ortega Aranegui, Ricardo
AB Osteogenesis imperfecta (OI) is a hereditary bone fragility disorder that in most patients is caused by mutations affecting collagen type I. Their typical oral and craneofacial characteristics (Dentinogenesis imperfecta type I and class III malocclusion), involve the dentist in the multidisciplinary team that treat these patients. It is usual to perform lateral skull radiographs for the orthodontic diagnosis. In addition, this radiograph is useful to analyse the junctional area between skull base and spine, that could be damaged in OI.Pathology in the craneovertebral junction (CVJ) is a serious complication of OI with a prevalence ranging from rare to 37%. To diagnosis early skull base anomalies in these patients, previously the neurological symptoms have been appear, we make a simple cephalometric analysis of the CVJ. This method has four measurements and one angle. Once we calculate the values of the OI patient, we compare the result with the mean and the standard deviations of an age-appropriate average in healthy controls. If the patient has a result more than 2,5 SDs above the age appropriate average in healthy controls, we should to refer the patient to his/her pediatrician or neurologist. These doctors have to consider acquiring another diagnostic images to be used to determine cranial base measurements with more reliability. Thereby, dentists who treat these patients, must be aware of the normal radiological anatomy of the cervical spine on the lateral cephalogram.
PB Medicina Oral
SN 1988-8708
YR 2015
FD 2015-02-01
LK https://hdl.handle.net/20.500.14352/102215
UL https://hdl.handle.net/20.500.14352/102215
LA eng
NO Ríos-Rodenas M, de Nova J, Gutiérrez-Díez MP, Feijóo G, Mourelle MR, Garcilazo M, Ortega-Aranegui R. A cephalometric method to diagnosis the craniovertebral junction abnormalities in osteogenesis imperfecta patients. J Clin Exp Dent. 2015 Feb 1;7(1):e153-8
NO This work was supported by Grant No. AP123942013 from the Mutua Madrileña Foundation for Medical Research, Madrid
DS Docta Complutense
RD 19 jul 2024