RT Journal Article
T1 Morphogenesis of the human laryngeal ventricles
A1 Pascual-Font, Arán
A1 Rivas, Luis
A1 Hernández-Morato, Ignacio
A1 Rodriguez-Niedenführ, Marc
A1 McHanwell, Stephen
A1 Sañudo, José R.
A1 Viejo Tirado, Fermín
A1 Vázquez Osorio, María Teresa
AB Background: Two theories explain the origin of human laryngeal ventricles: (1) ventricles derive from the fifth pharyngeal pouches; (2) development independent from the pouches.Methods: In all, there were 21 serially sectioned human embryos from stages 15 to 23, and 11 fetuses of 9 to 18 weeks. Computer-aided 3-dimentional reconstructions were made.Results: The cranial part of the laryngeal sulcus and future vestibule expands from the pharyngeal floor between the third and fourth pharyngeal pouches during stages 15 and 16 (33-37 days). The primordia of the ventricles appeared at stage 18 (44 days) as 2 lateral swellings in the caudal end of the future vestibule, limited by the third pharyngeal pouches. Active epithelial expansion and subsequent canalization during late embryonic and early fetal periods finalizes their development.Conclusions: The laryngeal ventricles do not derive from the pharyngeal pouches but the median region of the pharyngeal floor between the third and fourth pharyngeal pouches and arches at the caudal end of the future vestibule.
PB Wiley
YR 2012
FD 2012-03-14
LK https://hdl.handle.net/20.500.14352/104463
UL https://hdl.handle.net/20.500.14352/104463
LA eng
NO Viejo F, Pascual-Font A, Rivas L, Hernández-Morato I, Vázquez T, Rodriguez-Niedenführ M, McHanwell S, Sanudo JR. Morphogenesis of the human laryngeal ventricles. Head Neck. 2013 Mar;35(3):361-9. doi: 10.1002/hed.22970. Epub 2012 Mar 14. PMID: 22419400.
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 29 sept 2024